The ability of indigenous rhizobia to nodulate a legume crop effectively was critical to successful establishment and growth of legumes. This study was aimed to evaluate the symbiotic effectiveness along with growth responses to varied conditionslike pH, salt, temperature, antibiotics, and carbon and nitrogen sourcesfor rhizobial isolates nodulating faba bean from Tahtay Koraro, northwestern Zo...

The severe adverse reaction to vitamin K1 injection is always remarkable and is thought to result from anaphylaxis. Paradoxically, however, some patients administered vitamin K1 injection for the first time have adverse reactions. Using beagle dogs, the present study tested the hypothesis that the response to vitamin K1 is an anaphylactoid reaction. The results showed that serious anaphylaxis-l...

One of the unique features of Helicobacter pylori is its ability to assimilate free-cholesterol (FC) into its membranes. Via FC assimilation, H. pylori strengthens the membrane lipid barrier and/or evades the host immune system. No previous studies, however, have investigated the FC uptake mechanisms of the H. pylori cell. Phosphatidylethanolamine (PE) is the most prevalent lipid component of b...

Nevirapine is a highly lipophilic and water insoluble non-nucleoside reverse transcriptase inhibitor used for the treatment of HIV-1 infection. Lymphoid tissue constitutes the major reservoir of HIV virus and infected cells in HIV-infected patients. Self-emulsifying drug delivery system, using long chain triglycerides, is a popular carrier of drugs due to their ability to transport lipophilic d...

A field experiment was conducted during the winter (rabi) seasons of 2017–18 and 2018–19 at Rajasthan College Agriculture, Maharana Pratap University Agriculture Technology, Udaipur, Rajasthan, to find out best integrated nutrient management strategy in barley (Hordeum vulgare L.). The correlation regression were studied between yield attributes as influenced by these treatments. laid a randomi...

Silymarin, a flavonolignan, derived from Silybum marianum, family Asteraceae has long been used as hepatoprotective remedy. Silymarin cytoprotective activities due to its antioxidant property and free radical scavenging activity. The pharmacokinetic studies of past three decades revealed that silymarin poor absorption, rapid metabolism especially by Phase II ultimately oral bioavailability. Que...

BACKGROUND AND THE PURPOSE OF THE STUDY Domperidone (DOM) is a dopamine- receptor (D(2)) antagonist, which is widely used in the treatment of motion-sickness. The pharmacokinetic parameters make DOM a suitable candidate for transdermal delivery. The purpose of the present investigation was to develop transdermal delivery systems for DOM and to evaluate their physicochemical characteristics, in ...

By means of enzymatic and autoradiographic techniques, it has been demonstrated that, 24 hr after a single dose of the antitumor amino acid N-phosphonacetyl-L-aspartic acid (PALA), (400 mg/kg i.p.; 1.15 mmol/kg) to C57BL x DBA/2 F1 mice, the agent accumulates in bone to a concentration of approximately 400 microM; this is 3000 times greater than the Ki of PALA for its target enzyme, aspartate c...

As reações de fixação fósforo (P) em solos tropicais está entre as principais limitações para a agricultura, exigindo quantidades adubações acima do requerido pelas culturas. Como fontes P são esgotáveis e esse é um elemento essencial, busca estratégias sustentáveis seu suprimento torna-se imprescindível. Desse modo, avaliamos aplicação pó rocha carbonatito (PR) combinado com superfosfato simpl...

EVALUATiON OF A new drug includes analysis of its tissue distribution. We have developed an improved method for solubilizing tissues that is not only rapid, but results in a homogeneous sample for counting. We had found that organs rich in connective tissue (heart, lung, skeletal muscle, urinary bladder, stomach, and intestinal wall) could not be completely disrupted by conventional techniques ...