Vascular disease affecting the spinal can cause substantial neurologic morbidity. Several vascular spinal cord ailments present as neurologic emergencies, and should thus be recognizable to the practicing neurologist. We review the epidemiology, presentation, management strategies, and prognosis of various pathologies, including infarction, dural arteriovenous fistula, arteriovenous malformatio...

Spinal cord analysis is an important problem relating to the study of various neurological diseases. We present a novel approach to spinal cord segmentation in magnetic resonance images. Our method uses 3D "deformable organisms" (DefOrg) an artificial life framework for medical image analysis that complements classical deformable models (snakes and deformable meshes) with high-level, anatomical...

Introduction: Functional MRI methods have been used to study sensorimotor processing in the Spinal cord. However, these techniques confront unwanted contributions to the measured signal from the physiological fluctuations. For the spinal cord imaging, most of the challenges are consequences of cardiac and respiratory movement artifacts that are considered as significant sources of noise, especi...

background: amylin and salmon calcitonin belong to the calcitonin family of peptides and have high affinity binding sites in the rat spinal cord. the aim of this study was to characterize receptors for amylin and salmon calcitonin functionally in the spinal cord of rats. we assessed the expression of c-fos in response to intraplantar formalin in the lumbar regions of the spinal cord in consciou...

  Background: Spinal cord injury (SCI) is a major clinical condition and research is commonly done to find suitable treatment options. However, there are some degrees of spontaneous recovery after SCI and gender is said to be a contributing factor in recovery, but this is controversial. This study was done to compare the effects of sexual dimorphism on spontaneous recovery after spinal cord inj...

BACKGROUND Effective treatments for degenerative and traumatic diseases of the nervous system are not currently available. The support or replacement of injured neurons with neural grafts, already an established approach in experimental therapeutics, has been recently invigorated with the addition of neural and embryonic stem-derived precursors as inexhaustible, self-propagating alternatives to...

Human embryonic stem cells (hESC) hold great promise for the treatment of patients with many neurodegenerative diseases particularly those arising from cell loss or neural dysfunction including spinal cord injury. This study evaluates the therapeutic effects of transplanted hESC-derived oligodendrocyte progenitors (OPC) and/or motoneuron progenitors (MP) on axonal remyelination and functional r...