: Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is an antibody-related astrocytic disease for which a specific GFAP antibody serves as biological marker. Indeed, cerebral spinal fluid positive and/or seropositivity important basis its diagnosis. However, because patients with autoimmune encephalitis or demyelinating diseases can have similar profile, termed overlapping synd...

Tanshinone IIA serves as a coenzyme for certain biochemical reactions, exhibiting various pharmacological effects in the treatment of neurological diseases including spinal cord injury (SCI), however, its working mechanism SCI is not clear. Based on previous research, we believe that tanshinone promotes survival and repair nerves after through such anti-inflammatory, antioxidant, prevention cel...

STUDY DESIGN Population-based retrospective descriptive study. OBJECTIVE To describe the number and therapeutic profile of patients with spinal stenosis at a large-scale community level using health insurance claims data. SUMMARY OF BACKGROUND DATA A few reports have documented the prevalence of spinal stenosis, and no report has described the therapeutic profile for spinal stenosis in a po...

Introduction: Spinal cord injury (SCI) is one of the most serious clinical diseases, which not only affects the patient's physical and mental status, but its effects will be spread to family and community. After severe spinal cord injury, astrocytes of the central nervous system (CNS) become reactive astrocytes, and play the main role of glial scar formation. The scar is a major obstacle to r...

Objectives: Nowadays, spinal cord lesions, specially its injury, is one of the diseases/injuries that human-being is been affected by. It not only causes irreversible economical/social/cultural problems & uncompensated costs to the patient’s family & society but also, makes active peoples to inactive & needy ones. Till now, there is no successful treatment for these patients so this ailment, it...

background: spinal cord injury (sci) imposes a significant burden on the social and marital life. here, we assessed the divorce rate and changes in marital status among a sample of iranian individuals with sci. methods: referred patients to brain and spinal cord injury research center were invited to participate in this cross-sectional investigation. the main exclusion criteria were coincidenta...

introduction: spinal cord injury (sci) is one of the most serious clinical diseases, which not only affects the patient's physical and mental status, but its effects will be spread to family and community. after severe spinal cord injury, astrocytes of the central nervous system (cns) become reactive astrocytes, and play the main role of glial scar formation. the scar is a major obstacle t...

MR imaging was performed on 21 patients who had high-grade myelographic block due to various diseases in all spinal compartments (extradural, intradural/extramedullary, and intramedullary) and in all portions of the spinal canal (cervical, thoracic, and lumbosacral). Loss of CSF pulsation artifacts due to significant compression of the spinal cord was demonstrated on non-motion-compensated T2-w...

Neurodegenerative diseases, such as Alzheimer's, Parkinson's, and spinal cord injuries amongst others pose significant challenges to modern Medicine. Traditional treatments often focus on symptom management rather than targeting the root causes of these conditions. However, advent Neuroregenerative Medicine represents a cutting-edge field that aims at restoring structure function nervous system...