BACKGROUND/AIMS Several countries are working to adapt clinical trial regulations to align the approval process to the level of risk for trial participants. The optimal framework to categorize clinical trials according to risk remains unclear, however. Switzerland is the first European country to adopt a risk-based categorization procedure in January 2014. We assessed how accurately and consist...

We examine the performance of Total Variation (TV) smoothing for processing of noisy Electrocardiogram (ECG) recorded by an ambulatory device. The TV smoothing is compared with traditionally-used bandpass filtering using ECG with artificially added noise, as well as with real-world noise obtained during physiological monitoring. The fundamental difference between TV smoothing and traditional ba...

The relationship between television (TV) viewing and overweight in children is likely to be influenced by the quality of measures used. We systematically reviewed studies related to overweight in children that had included a measure of TV exposure. Literature searches were conducted in MedLINE, PsychInfo, SportDiscus and ISIWeb of Science. Methods of assessing TV viewing were evaluated, includi...

INTRODUCTION Television (TV) viewing is popular among adults and children, and child TV-viewing time is positively associated with parent TV-viewing time. Efforts to limit the TV-viewing time of children typically target parent rule-setting. However, little is known about the association between parent TV-viewing practices and rule-setting. METHODS We used baseline height and weight data and ...

Nowadays, Cable TV operators provide their users multiple ways to watch TV content, such as Live TV and Video on Demand (VOD) services. In the last years, Catch-up TV has been introduced, allowing users to watch recent broadcast content whenever they want to. Understanding how the users interact with such services is important to develop solutions that may increase user satisfaction, user engag...

Methods Sixty-eight (68) patients (mean age 26.9±7.3 years) with Ebstein’s anomaly (Types A=18, A=3, B=21, B-C=2, C=15, D=9) underwent correction of TV incompetence. The atrialized ventricle, the TV and subvalvar apparatus were inspected to analyze the precise morphology, and determine which leaflet was the most mobile. In all, the atrialized right ventricle (RV) is incorporated into the contra...