Actinomycetes were isolated from marine sediment samples collected from the east coast of Chennai, Tamil Nadu, India. Well diffusion and agar plug methods were used for the evaluation of antibiotic production by these isolates against drug resistant Methicillin- resistant Staphylococcus aureus (MRSA) and vancomycin resistant Enterococci (VRE). The potential isolate VITBRK2 was mass cultured for...

Chitinases have huge potential applications and biological value in industries, they are used generating single cell proteins, sweeteners, insecticides, antifungal drugs, anti-cancer agents, biopesticides, food processing degrading agents for sea waste etc. the conversion of chitin a polysaccharide into monomers. Chitin is produced enormously biosphere annually from fungal walls, exoskeletons i...

Compost is a highly humified organic fertilizer, rich in nutrients and source of variety aerobic microorganisms, including actinomycetes, which develop response to different levels temperature, humidity, oxygen pH. Microbes growing on the compost are believed have ability produce extracellular hydrolytic enzymes. The purpose this study was determine thermophilic actinomycetes XM21 isolated from...

The tlrB gene from Streptomyces fradiae has been cloned and used to construct bifunctional Streptomyces-Escherichia coli shuttle vectors carrying the antibiotic resistance genes to kanamycin-neomycin, thiostrepton and tylosin as selection markers. In the same way, the tlrB gene was subcloned in plasmids including the apramycin resistance gene and the oriT sequence from the plasmid pSET152 to fa...

A novel endophytic actinomycete, designated strain NEAU-LZS-5(T), was isolated from the leaf of candelabra aloe (Aloe arborescens Mill) and characterized using a polyphasic approach. Analysis of the 16S rRNA gene sequence showed that strain NEAU-LZS-5(T) belongs to the genus Streptomyces and exhibited 99.51 and 97.37 % similarity to Streptomyces sedi YIM 65188(T) and Streptomyces specialis GW41...

Traditional three-domain fungal and bacterial laccases have been extensively studied for their significance in various biotechnological applications. Growing molecular evidence points to a wide occurrence of more recently recognized two-domain laccase-like multicopper oxidase (LMCO) genes in Streptomyces spp. However, the current knowledge about their ecological role and distribution in natural...

INTRODUCTION Streptomyces spp. are aerobic, Gram-positive bacteria of the order Actinomycetales, known for their ability to produce antimicrobial molecules such as streptomycin. Pneumonia due to Streptomyces is considered to be rare and limited to immunocompromised patients. Streptomyces spp. are only rarely associated with invasive systemic infections. To our knowledge, we report the first doc...

The paulomycins are a group of glycosylated compounds featuring a unique paulic acid moiety. To locate their biosynthetic gene clusters, the genomes of two paulomycin producers, Streptomyces paulus NRRL 8115 and Streptomyces sp. YN86, were sequenced. The paulomycin biosynthetic gene clusters were defined by comparative analyses of the two genomes together with the genome of the third paulomycin...

Streptomyces albus is the type species of the genus Streptomyces. Here, we report the draft genome sequence of S. albus strain NBRC 13014(T). The genome contains at least seven orphan polyketide synthase and nonribosomal peptide synthetase gene clusters. The genome sequence will also serve as a valuable reference for Streptomyces taxonomy.