Unani medicine relies on drugs of natural origin for the treatment various medical conditions. It is practised throughout Asia and particularly in India. The rich drug asset includes both single compound drugs. Habb-e-Azaraqi a polyherbal formulation used clinically since decades management neurological disorders like facial palsy, paralysis, gout arthritis. explicit nature rationalizes its use...

Brucine. 2.3-Dimethoxystrychnidin-10-one was extracted from the seeds of Strychnos nux-vemica. L as described earlier (3,7). The crude alkaloid was crystallized from ethyl alcohol. melting at 178°C, The iso'lated cockroach heart technique described by Krijgsman et at. (2) was employed for the present studies. In all the experiments only adult insects were used. Sexual differences and age factor...

Fractionation of an antitrypanosomal lipophilic leaf extract from Strychnos spinosa led to the isolation of eight triterpenoids and sterols in this plant part for the first time. Two of these were found to possess in vitro antitrypanosomal activity, namely, saringosterol (14) and 24-hydroperoxy-24-vinylcholesterol (15), with IC(50) values of 7.8 +/- 1.2 and 3.2 +/- 1.2 microM, respectively. The...