Strychnos henningsii Gilg is recommended among other remedies for the treatment of diabetes in traditional medicine of Southern Africa. The antidiabetic effect of oral administration of aqueous bark extract of the plant at 125, 250 and 500 mg/Kg body weight was investigated in diabetic rats induced with streptozotocin-nicotinamide for 15 days. The extract decreased the blood glucose level, feed...

strychnos henningsii gilg is recommended among other remedies for the treatment of diabetes in traditional medicine of southern africa. the antidiabetic effect of oral administration of aqueous bark extract of the plant at 125, 250 and 500 mg/kg body weight was investigated in diabetic rats induced with streptozotocin-nicotinamide for 15 days. the extract decreased the blood glucose level, feed...

Strychnos henningsii Gilg is recommended among other remedies for the treatment of diabetes in traditional medicine of Southern Africa. The antidiabetic effect of oral administration of aqueous bark extract of the plant at 125, 250 and 500 mg/Kg body weight was investigated in diabetic rats induced with streptozotocin-nicotinamide for 15 days. The extract decreased the blood glucose level, feed...

Strychnos henningsii Gilg is recommended among other remedies for the treatment of diabetes in traditional medicine of Southern Africa. The antidiabetic effect of oral administration of aqueous bark extract of the plant at 125, 250 and 500 mg/Kg body weight was investigated in diabetic rats induced with streptozotocin-nicotinamide for 15 days. The extract decreased the blood glucose level, feed...

ETHNOPHARMACOLOGICAL RELEVANCE Traditional medicines play an important role in the management of chronically painful and debilitating joint conditions, particularly in the rural Africa. However, their potential use as sources of medicines has not been fully exploited. The present study was carried to find the medicinal plants traditionally used to manage chronic joint pains in Machakos and Maku...

The polysaccharides and proteins of various seeds have bioflocculant properties. The performance of naturally occurring Strychnos potatorum was evaluated against the chemical coagulant alum. The study involved extensive jar test experiments using Strychnos potatorum suspension and alum solution either independently or in combination with spiked turbid water prepared in the laboratory. It was ob...

Plants in Kenya are becoming increasingly important as sources of traditional medicines. The World Health Organization (WHO) has estimated that malaria kills about 2.7 million people every year, 90% of who are from Africa. Malaria continues to be a national concern in Kenya as it plays a major role in the high mortality rates being experienced currently. The use and mis-use of chloroquine to pr...

Four new bisindole alkaloids of the Strychnos-Strychnos type, leucoridines A-D (1-4), were isolated from the stem-bark extract of Leuconotis griffithii. Alkaloids 1-4 showed moderate cytotoxicity against drug-sensitive and vincristine-resistant human KB cells.

In considération of thé many biological properties of alkaloids, and particularly of quinine (which remains an important antimalarial drug), it was not surprising that a séries of indolomonoterpenic alkaloids, mainly isolated from Strychnos usambarensis Gilg and from Strychnos icaja Baill., thé latter used in traditional medicine from Central Africa to treat chronic malaria, présent antiplasmod...