BACKGROUND Adverse childhood experiences have been described as one of the major environmental risk factors for depressive disorder. Similarly, the deleterious impact of early traumatic experiences on depression seems to be moderated by individual genetic variability. Serotonin transporter (5-HTT) and brain-derived neurotrophic factor (BDNF) modulate the effect of childhood adversity on adult d...

INTRODUCTION We present the results of a two-experiment study designed to evaluate the neurocognitive and psychological effects of six-degree head-down bedrest and pharmacologic interventions (3,5,3'-triiodothyronine; T3) implemented to enhance the muscle and bone atrophy associated with simulated microgravity. Subsequently, the effects of countermeasures (alendronate and testosterone) administ...

Abbreviations: APACHE: Acute Physiology and Cronic Health Evaluation; CAPS: Clinician Administered PTSD Scale; DTS: Davidson Trauma Scale; GCS: Glasgow Coma Scale; HADS: Hospital Anxiety and Depression Scale; HRQoL: Health Related Quality of Life; IES: Impact of Events Scale; IES-R: Impact of Events Scale-Revised; ICU: Intensive Care Unit; ISS: Injury Severity Score; LOS: length of Stay; MV: Me...

Persisting gastroesophageal reflux disease (GERD) symptoms affect mental state and social activities and mental disorders likewise play a crucial role on GERD symptoms. The aim of this study was to analyze the data of Symptom Checklist by 90-Revised (SCL-90-R) questionnaire in patients with persisting GERD symptom and to explore the impact of psychological factors on them.The patients accepted ...

Symptom management is one of the predominant components of HIV/AIDS care. Frameworks that adequately posses sufficient construct validity and that reflect the symptom experience related to HIV disease, treatment, and medications have been limited. Without validated measures, nurses and other care providers are limited in their ability to accurately assess symptomology and to make appropriate ch...

OBJECTIVE To investigate whether thought field therapy (TFT) has an impact on anxiety symptoms in patients with a variety of anxiety disorders. DESIGN Forty-five patients were randomized to either TFT (n = 23) or a waiting list (n = 22) condition. The wait-list group was reassessed and compared with the TFT group two and a half months after the initial evaluation. After the reassessment, the ...

The current study examined the 3-year longitudinal course of psychopathology reported by 53 definite MS patients, then assessed for clinical elevations. Across SCL-90-R scales, only 9-21% of patients' scores changed. Intercorrelations among Time 1 and Time 2 were significant (p < .01). Clinical elevations on the scales ranged from 26% (anxiety) to 52% (somatization). Consistent with studies of ...

BACKGROUND Prisoners are at risk of mental disorders. Therefore attention to mental health of prisoners is important. OBJECTIVES This study aimed determine to the prevalence of mental disorders among Kashan prisoners. PATIENTS AND METHODS This cross sectional study was carried out in Kashan prison (Iran). 180 Subjects were selected by using stratified random sampling and evaluated with Symp...