Background: Erythropoietin (EPO) was first known as a factor for red blood cell proliferation and differentiation. New studies show the effects of EPO on immune system. Objective: In this study, the effects of pretreatment with recombinant human erythropoietin (rHuEPO) on the anti-human leukocyte antibody (anti-HLA) titer were determined. Methods: Three groups of rats were sensitized with human...

background: in some studies inflammatory bowel disease (ibd) and celiac disease were considered to be associated and some belive that this association may influence the prognosis of ibd. however, there is a cosiderable controversy regarding this association. therefore ,we aimed to assess the association of these two common digestive diseases and evaluate the complications of this association. m...

recently, using polymerase chain reaction (pcr) technique, the dna of cytomegalovirus was detected from depigmented white patches in patients with vitiligo. the reactivation of infection and occasional anti-cmv igm circulating among patients infected by cytomegalovirus has been reported for years. we have studied 26 patients with clinical signs and symptoms of vitiligo, some of whom had a histo...

in this research, gold nanoparticles were synthesized and functionalized by the antibody of aflatoxins. the quenching of the fluorescence of excitation emission matrices (eem) of two type of aflatoxins (b1, g1), provoked by the gold nanoparticles, was studied by principal component analysis (pca) and multivariate curve resolution with alternating least squares (mcr-als). these aflatoxins show q...

the central immunological disturbance in systemic lupus erythematosus (sle) is autoantibody production. some of these antibodies affecting components of the cell nucleus are the major characteristics of sle. the present study was aimed to assess importance of anticardiolipin (acl) antibody and its association with clinical state in sle patients. a cross sectional study was performed on 100 pati...

the serious influenza-associated complications among immunodeficient individuals such as those who are infected with human immunodeficiency virus (hiv), highlights the importance of influenza vaccination in these people. therefore, the current study aimed to investigate the antibody responses to influenza vaccine in this group. two hundred subjects were recruited, during autumn 2010 and 2011, t...

different igg subclass profiles are produced in response to different antigenic stimuli in a variety of diseases. igg subclass levels may reflect disease severity. quantification of igg subclasses depends on the availability of specific monoclonal antibodies (mabs). in the present study seven hybridoma clones producing mabs reactive with multiple subclasses of human igg were established. spleno...

background: infertility is one of the common problems seen in couples of reproductive age. presence of antisperm antibodies in semen and serum are amongst the causes of immunoinfertility. this study was performed to determine antisperm antibodies in cervicovaginal secretions and serum of infertile women and also measure serum levels of immunoglobulins (igg, igm and iga). methods: the study cons...

objective: this study aimed to assess the value of chlamydia trachomatis (c.trachomatis) antibodytiter test in prediction of  tubal damage. materials and methods : in this case-control study we enrolled50 women with tubal factor infertility (proven by laparoscopy after hysterosalpingography) and 110 women without infertility history. elisa was performed for all participants, seeking c.trachomat...