Neural stem cells are undifferentiated cells that are located in limited areas of central nervous system. These cells have proliferation and self-renew ability and can be differentiated into neurons and glial cells. Mature nerve cells do not have proliferative ability; and due to the limited number of nerve stem cells, injuries to the nervous system are not recoverable. The purpose of this revi...

objective(s): intestinal ischemia-reperfusion is a major problem, which may lead to multiorgan failure and death. the aim of this study was to evaluate the protective effects of dexmedetomidine on cell proliferation, antioxidant system, cell death, and structural integrity in intestinal injury induced by ischemia-reperfusion in rats. materials and methods: animals were randomized into three gro...

background nicotinamide (na), the active form of vitamin-b3, is hypothesized to have positive effects on the process of wound healing; it has anti-inflammatory, antioxidant, and immunomodulatory properties, as well as an epithelization inducing action. objectives in the present study, we aimed to determine the effects of topical administration of na on skin wounds, based on histomorphometrical ...

Background:As the use of mobile phones is increasing, public concern about the harmful effects of radiation emitted by these devices is also growing. In addition, protection questions and biological effects are among growing concerns which have remained largely unanswered. Stem cells are useful models to assess the effects of radiofrequency electromagnetic fields (RF-EMF) on other cell lines. S...

stem cells are of great interest for regenerating disturbed tissues and organs. these cells are commonly isolated from the bone marrow, but there has been interest in other tissues in the recent years. in this study, we evaluated the possibility of isolation of stem cells from oral connective tissue and investigated their characteristics.in this experimental study, sampling from the bone marrow...

TNF-α is a multifunctional cytokine that regulates cell proliferation and differentiation, as well immunological host defense responses to infection. It also induces angiogenesis, modulates tissue remodeling, controls apoptosis.TNF-α pleiotropic, pro-inflammatory has the potential be both pro-tumorigenic anti-tumorigenic. can cytotoxic tumour cells, slowing progression or causing necrosis, it e...

human diploid fibroblast cells produce a spectrum of necessary growth factors and extracellular matrix (ecm) components essential for growth and proliferation of a variety of other cell types. in this study, the effect of five human embryonic fibroblast cell lines, isolated from liver, lung, skin and foreskin tissues, was investigated. a coculture system analyse was employed to cloning efficien...

Abstract Objective To explore the role and possible regulatory mechanisms of ATP5B in colorectal cancer. Methods Online databases were used to analyze expression prognosis patients with l The data TCGA database analyzed by Gene Set Enrichment Analysis. Co‐expression network analysis was coexpedia. Colorectal cancer cell (SW480 DLD1) transfected small interfering RNA validated real‐time fluoresc...