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دانشگاه علوم پزشکی اصفهان

[ 1 ] - ساخت و مشخصه‌یابی غشای پلی‌کاپرولاکتون‌فومارات- ژلاتین الکتروریسی شده برای کاربرد بازسازی هدایت شده‌ی بافت پریودنتال

غشاهای مسدود کننده به منظور بازسازی بافت هدایت شده پریودنتال در دندان پزشکی، استفاده میشوند. هدف از این پژوهش، ساخت و مشخصه یابی غشای پلی کاپرولاکتون فومارات- ژلاتین به روش الکتروریسی برای کاربرد بازسازی بافت پریودنتال بود. ابتدا پلیکاپرولاکتوندیال و پلیکاپرولاکتون فومارات ساخته شد و به وسیله ی آزمایشات طیف سنجی تشدید مغناطیسی هسته(HNMR)، طیف سنجی فروسرخ فوریه(FTIR) و کروماتوگرافی ژل تراوا...

[ 2 ] - Comparison of the efficacy of Piascledine and transforming growth factor β1 on chondrogenic differentiation of human adipose-derived stem cells in fibrin and fibrin-alginate scaffolds

Objective(s):The aim of this study was to compare the chondrogenic induction potential of Piascledine and TGF-β1 on adipose-derived stem cells (ADSCs) in fibrin and fibrin-alginate scaffolds. Materials and Methods: Human subcutaneous adipose tissues were harvested from three patients who were scheduled to undergo liposuction. Isolated ADSCs were proliferated in a culture medium. Then, the cell...

[ 3 ] - Review Paper: Adipose Tissue, Adipocyte Differentiation, and Variety of Stem Cells in Tissue Engineering and Regeneration

Human adipose tissue represents an abundant, practical and appealing source of donor tissue for autologous cell replacement. Recent findings have shown that stem cells within the stromalvascular fraction of adipose tissue display a multilineage developmental potential. Adipose tissue-derived stem cells can be differentiated towards adipogenic, osteogenic, chondrogenic,myogenic and neurogenic li...

[ 4 ] - A Review Study: Effect of Growth Factors on Human Mesenchymal Stem Cells Differentiation into Cartilage Tissue

Hyaline cartilage is a vascular and neural tissue with scanty chondrocytes and limited regenerative ability. After some serious injuries of the cartilage, healing process will take place through the formation of fibrocartilage structures. Currently, tissue engineering and cell therapy are 2 interesting therapeutic fields dealing with regenerative medicine. In this regard, tissue&...

[ 5 ] - مقایسه بیان ژن اگریکان در کندروژنز سلول‌های بنیادی مشتق از چربی در دو سیستم کشت Pellet و Micromass

Background: Nowadays, Human adipocyte-derived stem cells (hADSCs) has been widely used in tissue engineering because of its unique features such as extraction from more sources, more easily and non-invasive extraction methods. In order to increase cell-cell interactions, similar to embryonic pre-cartilage condensation, the use of three dimensional (3D) high-density cell culture systems such as ...

[ 6 ] - In Vitro behavior of mechanically activated nanosized Si-Mg-doped fluorapatite

Hydroxyapatite (HA) is perhaps the most attractive material for bone repair, replacement and regeneration, due to its chemical composition and crystallographic structure which are similar to those of natural bone mineral. However, replacement of various elements and compounds in HA, could improve biological properties of this material. The aim of this study was preparation, characterization and...

[ 7 ] - Effects of Formative Assessment on Medical Students’ Learning Outcomes in Anatomy and Histology Courses in Isfahan University of Medical Sciences

Introduction: Research has shown that formative assessment along with summative assessment improves quality of education, motivation to study, and self-directed learning among students. This study aimed to examine the effects of formative assessment as well as summative assessment on medical students’ learning outcomes in anatomy and histology courses in Isfahan University of Medical Sciences. ...

[ 8 ] - Effects of RF-EMF Exposure from GSM Mobile Phones on Proliferation Rate of Human Adipose-derived Stem Cells: An In-vitro Study

Background:As the use of mobile phones is increasing, public concern about the harmful effects of radiation emitted by these devices is also growing. In addition, protection questions and biological effects are among growing concerns which have remained largely unanswered. Stem cells are useful models to assess the effects of radiofrequency electromagnetic fields (RF-EMF) on other cell lines. S...

[ 9 ] - Comparison of Fibrin and PLGA/fibrin Scaffolds for Chondrogenesis of Human Adipose Derived Stem Cells by Icariin

Background: Recently, cartilage tissue engineering is the best candidate for regeneration of cartilage defects. We evaluated the potential of fibrin and PLGA/fibrin scaffolds in providing a suitable environment for growth and chondrogenic differentiation of human adipose derived stem cells (hADSCs) in the presence of icariin. Method: The Three-dimensional...

[ 10 ] - Which Culture System Is better for Chondrogenesis of Adipose-Derived Stem Cells ; Pellet or Micromass?

Background and Aims: The current study was conducted to compare the expression levels of collagen type Π and X during chondrogenesis of human adipose-derived mesenchymal stem cells (hADMSCs) pellet and micromass cultures. Materials and Methods: Extracted hADMSCs were cultured until three passages and then transferred to pellet and micromass cultures in the experimental groups of day 7 and day...

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