نتایج جستجو برای: transdermal drug delivery
تعداد نتایج: 751261 فیلتر نتایج به سال:
Background: Nowadays transdermal drug delivery systems (TDDS), as an appropriate replacement for oral and parenteral dosage forms, are developing. These systems which designed to transport drugs through skin layers into the systemic circulation, have several benefits such as avoiding first-pass metabolism, sustained and controlled drug release, reducing side effects, and ease of use. The aim of...
The paper focuses on the advances in the field of pain treatment by transdermal delivery of specific drugs. Starting from a short description of the skin barrier, the pharmacodynamics and pharmacokinetics including absorption, distribution, action mechanism, metabolism and toxicity, aspects related to the use of pain therapy drugs are further discussed. Most recent results on topical anesthetic...
The purpose of the present study was to explore the passive and electrically assisted transdermal transport of Granisetron hydrochloride (GRA) in solution and gel formulation through iontophoresis and also the feasibility of delivering therapeutic amounts of drug for the treatment of chemotherapy-induced nausea and vomiting. In this study, iontophoretic permeation of GRA through guinea pig...
Transdermal drug delivery is the application of drug on the skin surface so that it can permeate through the skin and reaches the systemic circulation at sufficient concentration to ensure therapeutic efficacy. Transdermal drug delivery system (TDDS) has several advantages over conventional system; TDDS offers sustained drug release, avoidance of first pass effect, patient compliance, ease of a...
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