Background: Teriparatide is a new agent serves as a treatment of choice for severe post-menopausal osteoporotic patients who are at a high risk of fracture or have failed or been intolerant of previous osteoporosis therapy. The objective of this study is estimating the cost-utility of Teriparatide compared with no treatment from health system perspective in Iran. Method: A microsimulation...

A cost-utility analysis, based on published data from multiple observational studies, comparing boys circumcised at birth and those not circumcised was undertaken using the Quality of Well-being Scale, a Markov analysis, the standard reference case, and a societal perspective. Neonatal circumcision increased incremental costs by $828.42 per patient and resulted in an incremental 15.30 well-year...

This paper defines a new utility importance of a state of a component in multi-state systems. This utility importance overcomes some drawbacks of a well-known importance measure suggested by William S. Griffith (J. Applied Probability, 1980). The relationship between this new utility importance and the Griffith importance is studied and their difference is illustrated with examples. The contrib...

Although it is well recognised that ontologies have an important role to play in data integration, the lack of established ontologies in domains of interest often makes ontology-based integration a difficult task. Previous research on ontology design methodologies shows that manual construction of ontologies is a complex process and it is very hard for a designer to develop a consistent ontolog...

BACKGROUND The influence of patient preference and treatment costs has not been considered in previous analyses of wound management decisions for contaminated right lower quadrant incisions. STUDY DESIGN We performed a decision and cost-utility analysis, conducting a MEDLINE search of the postappendectomy wound infection literature to establish assumptions and assign baseline probability esti...

Concrete efforts to integrate Software Engineering and Human Computer Interaction exist in the form of models by many researchers. An unconventional model called TEIM (The Evolved Integrated Model) of Software Engineering and Human Computer Interaction was proposed by us. There is a need to establish correlation with prior models as well validate utility of TEIM. In this paper product PS design...

Many expensive treatments have been developed for Parkinson's disease (PD), and a good cost-utility analysis is required. Quality-adjusted life-years (QALY) allows comparison of the cost-utility of different medical conditions. If a treatment strategy gives a patient an extra but unhealthy year, the QALY he obtained will be less than one. When a therapeutic strategy is more effective, but cause...

Educational needs assessments (hereafter NAs) are inattentive to cost considerations and are frequently dominated by elite stakeholder groups. In this article I make a case for adopting a cost-utility approach, illustrating the argument with data generated in a NA of central library services in a Canadian school district. Using survey data from eight stakeholder groups, I found that (1) NAs bas...