Objective: To establish the quality standard for Penyankang Suppository. Method: Thin Layer Identification (TLC) was used for the qualitative identification of Caulis Sargentodoxae, Radix Salviae Miltiorrhizae, Rhizoma Corydalis and Rhizom Sparganii. High performance liquid chromatography (HPLC) was used to determine the contents of salvianolic acid B and tetrahydropalmatine. Results: Thin Laye...

The rectal route has proven its worth in terms of achieving successful drug delivery both locally and systematically. primary goal this invention was to develop evaluate Flax suppositories. To administer herbal powder internal sites, suppositories are placed directly into the rectum. A suppository comprises flax as a main active ingredient, administered through route, used laxative, treatment h...

TRIAL DESIGN: To compare the difference in pain score during flexible cystoscopy between patients undergoing the procedure with plain lubricating gel  only and plain gel with diclofenac suppository in a randomized control trial. METHODS:  A total of 60 male patients with an indication of flexible cystoscopy were enrolled in a prospective, randomized controlled study. Patients were randomized in...

INTRODUCTION The effectiveness of HIV pre-exposure prophylaxis (PrEP) requires consistent and correct product use, thus a deeper understanding of women's stated product formulation preferences, and the correlates of those preferences, can help guide future research. VOICE-D (MTN-003D), a qualitative ancillary study conducted after the VOICE trial, retrospectively explored participants' tablet a...

BACKGROUND Mesalazine suppositories are recommended and widely used as the standard therapy in induction and maintenance of remission for proctitis. AIM To evaluate the efficacy of mesalazine suppositories in patients with ulcerative colitis (UC) and rectal inflammation; and in patient groups categorised by the extent of lesions. METHODS This study was a phase III multicentre, randomised, d...

The aim of this research was to study the effect of exogenous interleukin (IL)-8, IL-1 and IL-8 + IL-1 on uterine contractions in rabbits. Four equal groups of non-pregnant rabbits (n = 24) were investigated using either placebo or experimental drugs in the form of vaginal suppositories. The suppositories contained human recombinant IL-8 (200 ng), IL-1 (200 ng), IL-8 (200 ng) + IL-1 (200 ng) or...