BACKGROUND The aim of this study is to observe the inhibitive effects of p66Shc gene interfering lentivirus vectors on the expression of p66Shc, and to explore its effects on alveolar epithelial cells apoptosis induced by hyperoxia. METHODS The gene sequences were cloned into the pLenR-GPH-shRNA lentiviral vector, which was selected by Genebank searches. The pLenR-GPH-shRNA and lentiviral vec...

e18644 Background: Assessments of health-related quality life (HRQOL) are conducted by health systems to analyze and improve patient-centered care. Numerous studies have shown that the COVID-19 pandemic poses unique stressors for patients with cancer. However, impact on HRQOL in cancer is unknown. This study investigates change self-reported global scores before during pandemic. Methods: In thi...

Abstract. Dry conditions associated with the El Niño–Southern Oscillation (ENSO) and a positive Indian Ocean Dipole (IOD) are known to have caused major fire pollution events intense carbon emissions over vast spatial expanse of Indonesia in October 2006 2015. During these two events, substantial increase monoxide (CO) mixing ratio was detected by situ measurements at Lulin Atmospheric Backgrou...

Background The second COVID-19 vaccination in autoimmune disease (COVAD-2) study [1] is an international, multicentre, self-reported e-survey designed to evaluate several facets covering infection and as well validated patient-reported outcome measures (PROMs) a variety of diseases (AIDs), including systemic sclerosis (SSc). Detailed assessment the health-related quality life (HRQOL) its driver...

Abstract Background Impact of recurrent pericarditis (RP) on patient health-related quality life (HRQoL) was evaluated through qualitative interviews and as an exploratory endpoint in a Phase 2 trial evaluating the efficacy safety rilonacept (IL-1?/IL-1? cytokine trap) to treat RP. Methods Qualitative were conducted with ten adults RP understand symptoms HRQoL impacts, 10-item Patient-Reported ...

آلیاژهای منیزیم معمولاً دارای عدم تقارن تسلیم در حالت کشش و فشار هستند که این عامل ناشی از سازوکارهای مختلف تغییر شکل پلاستیک فعال تحت بارگذاری‌های کششی فشاری است. مقاله بر روی شبیه‌سازی المان حجمی نماینده‌ی سه‌بعدی آلیاژ اکسترود شده تمرکز دارد تا با کمک روابط کریستال پلاستیسیته تأثیر شدت بافت پایه ـ را بررسی کند. پلاستیسته مبتنی‌بر لغزش به‌صورت یک زیربرنامه نرم‌افزار آباکوس (U‌M‌A‌T) برای آزمون...

The standing spin wave resonance has been measured in thin films of EuS at 1.1 OK in the perpendiculai configuration. The magnon dispersion relation is found to be quadratic in the observed region of k (k < 0.2 xla). The effective exchange energy (JI $. Jz) determined is 0.088 f 0.010 OK. This value is lower than that calculated by Passenheim et al. [7] from specific heat measurements. This dis...

هدف: تخمین شناختی تلاش برای ارائه یک پاسخ معقول براساس اطلاعات در دسترس است. هدف از این مطالعه طراحی آزمون و بررسی روایی، پایایی مقادیر هنجار آن روش: 643 نفر دانشجویان دانشگاه شهید بهشتی انجام شد. آزمون‌های شده حاضر، مرتب کردن کارت­‌های ویسکانسین، رنگ واژه استروپ حافظه فعال چند محرک پیشین به عنوان آزمون­‌های کارکرد اجرایی همزمان ارزیابی مورد استفاده قرار گرفت. همبستگی پیرسون روایی همزمان، تی مق...