Introduction: Hospital acquired infections (HAI) are the number four cause of death in the United States at an annual cost estimated at $40 billion. With emerging scienti c data regarding the contribution of air contamination to surgical site infections (SSI), there is increased interest in considering innovative adjunctive technologies to support best air quality in operating rooms (ORs). Obje...

The objective of this study was to test the inactivation efficiency of two different light-based treatments, namely ultraviolet B (UVB) and ultraviolet C (UVC) irradiation, on Pseudomonas aeruginosa biofilms at different growth stages (24, 48, and 72 h grown). In our experiments, a type of AlGaN light-emitting diodes (LEDs) was used to deliver UV irradiation on the biofilms. The effectiveness o...

This work presents the comparison of four advanced oxidation processes driven by UVC-LED radiation (278 nm—2 W/m2) for simultaneous bacteria inactivation (Escherichia coli—106 CFU/mL) and microcontaminant removal (imidacloprid—50 µg/L) in simulated wastewater secondary effluent. To this end, activation H2O2 S2O82− as precursors HO• SO4•−, respectively, UVC-LED/Fe3+–NTA (ferric nitrilotriacetate...

There is conflicting evidence for the role of the mismatch repair (MMR) genes hMLH1 and hMSH2 in the transcription-coupled repair (TCR) pathway of nucleotide excision repair. In the present work, we have examined the role of these MMR genes in nucleotide excision repair using two reporter gene assays. AdHCMVlacZ is a replication-deficient recombinant adenovirus that expresses the beta-galactosi...

To cope with ultraviolet C (UVC)-stalled replication forks and restart DNA synthesis, cells either undergo DNA translesion synthesis (TLS) by specialised DNA polymerases or tolerate the lesions using homologous recombination (HR)-based mechanisms. To gain insight into how cells manage UVC-induced stalled replication forks, we analysed the molecular crosstalk between the TLS DNA polymerases Polη...

This letter presents a novel realization of a voltage-mode (VM) first-order all-pass filter (APF) with attractive features. The proposed circuit employs a single readily available six-terminal active device called as universal voltage conveyor (UVC) and only grounded passive components, which predict its easy monolithic integration with desired circuit simplicity. The auxiliary voltage input (W...