The ethyl acetate soluble fraction from the roots of Sanguisorba tenuifolia was found to have a hypoglucemic effect in alloxan-induced diabetic rats. Two new triterpenoids, identified as 2-oxo-3β,19α-dihydroxyolean-12-en-28-oic acid β-D-gluco-pyranosyl ester (1) and 2α,19α-dihydroxy-3-oxo-12-ursen-28-oic acid β-D-glucopyranosyl ester (4) were isolated from this fraction, along with thirteen kno...

Multiple effects of ozone are a prerequisite for its use in the complex therapy inflammatory bowel diseases. Our aim was to analyze and 5-aminosalicylic acid (5-ASA) oxazolone-induced colitis (OIC) upon innate immunity functions.
 OIC modeled 72 male Wistar rats weighing 24020 g by two-stage application oxazolone solution. Ozone at dose 0.05 mg/kg, as part ozone-oxygen mixture, injected in...

Objective: <i>Jowiseunggi-tang</i> (JWSGT) is a traditional herbal medicine commonly used for purgative activity in constipation. This study evaluates JWSGT the treatment of opioid-induced constipation (OIC), most common and debilitating gastrointestinal effect opioid use.Methods: A 64-year-old man with floor mouth cancer was hospitalized OIC, administered orally twice day 10 days, ...

one of the basic tenets in recent international trade literature is about the effect of trade integration on business cycle synchronization (bcs) among trading countries. the objective of this paper is to explore the main determinants of business cycle synchronization, with emphasis on trade integration. to this end, we have specified two simultaneous regression equations which were estimated b...

The exchange rate plays an essential role for firms which export goods and import raw materials. In this paper, the effects of real specific exchange rate fluctuations in imports, exports and aggregate trade on industry sector, chemical and transportation industries outputs in 49 OIC countries were investigated by using a panel data model over 1990-2014. Particularly, this paper presents eviden...

BACKGROUND In health economic evaluations, quality of life should be measured with preference-based utilities, such as the EuroQol 5 Dimension 3-level (EQ-5D-3 L). Non-preference-based instruments (often disease-specific questionnaires) are commonly mapped to utilities. We investigated if the relationship observed between the Patient Assessment of Constipation Quality of Life (PAC-QOL) and the ...