A significant challenge to the application of evolutionary multiobjective optimization (EMO) for transonic airfoil design is the often excessive number of computational fluid dynamic (CFD) simulations required to ensure convergence. In this study, a multiobjective particle swarm optimization (MOPSO) framework is introduced, which incorporates designer preferences to provide further guidance in ...

The present work is part of a wide research project aimed to elucidate the mechanism of the metabolic activation of the antitumor imidazoacridinone agent C-1311 selected for clinical trials. The objectives of the investigations presented here were: (i) to examine the enzymatic transformation of the reference compound 2-hydroxyacridinone and (ii) to test the similarity between enzymatic and elec...

This case study attempted to investigate the factors underlying difficulties PMU Saudi, undergraduate, male students encountered in writing traditional, argument essays for a core, course (COMM 1311) they took fall semester of 2017/2018. Using purposive sampling technique and structured interviews collect data, researcher interviewed male, who course. Data saturation was achieved as result thir...

BACKGROUND A program for outpatient and intermediate inpatient care for the homeless was pioneered by the humanitarian organization Médecins Sans Frontières (MSF) in Milan, Italy, during the winter of 2012-2013. We aimed to document the characteristics and clinical management of inpatients and outpatients seen during this program. METHODS A clinic providing outpatient and intermediate inpatie...

Thyrotoxicosis is a clinical syndrome due to excessive amounts of thyroid hormone in the circulation and tissues. Graves' disease, goitre and exophthalmos, is the commonest variety, but in some parts of the world thyrotoxicosis supervenes on the background of a long standing nodular goitre. Other varieties such as ectopic TSH syndromes are very rare. The diagnostic sequence in practice starts w...