BACKGROUND AND PURPOSE Wilson's disease (WD), also known as hepatoleticular degeneration (HLD), is a rare autosomal recessive genetic disorder of copper metabolism, which causes copper to accumulate in body tissues. In this study, rats fed with copper-laden diet are used to render the clinical manifestations of WD, and their copper toxicity-induced organ lesions are studied. To investigate meta...

In this paper we designed and prepared three free-metal organic days Dye 1, Dye 2 and Dye 3 based on indoline with n-phenly substituents iminodibenzyl as the electron donor group. We used cyanoacrylic acid substituent as the electron acceptor anchoring group in organic dyes. The proposed dyes were prepared from iminodibenzyl as the starting material by standard reactions and characterized by di...

The negative impact of heat stress (HS) on the production performances in pig faming is of particular concern. Novel diagnostic methods are needed to predict the robustness of pigs to HS. Our study aimed to assess the reliability of blood metabolome to predict the sensitivity to chronic HS of 10 F1 (Large White × Creole) sire families (SF) reared in temperate (TEMP) and in tropical (TROP) regio...

Systematic research has been conducted on the products of catalytic oxyethylenation of lanolin. The level of hydrophilic-lipophilic balance HLB and the amount of oxyethylene segments nTE in homologous series of products were determined by means of the 1HNMR method. Viscosity and spectrophotometry measurements were used to determine solubilization indices n/s/, the micellar partition coefficient...

Melting points were obtained on Veego VMP-1 apparatus in open capillary tubes and are uncorrected. The reactions were monitored by TLC on silica gel thin layer plates. Compounds were analyzed for C, H, N and analytical results obtained for these elements were within ±0.5% of the calculated values for the formula shown. IR spectra were obtained using a Perkin Elmer spectrum-2 FT-IR spectrometer....

Some new isatin3hydrazone derivatives that are Isatin3(benzylidene)hydrazone, Isatin3-(methyl ethylide)hydrazone, isatin 3-(isoproplylidene)hydrazone have been synthesized from the reaction of isatin3-hydrazone and different aldehydes and ketones. Thestructure of synthesized compound is assigned on the basis of, IR, 1HNMR, 13CNMRdata. The anti microbial activity was done by disk diffusion metho...

The novel Ligand was prepared by irradiation of 2-amino-1-methyl benzimidazole and 3’,5’-dimethoxy-4'-hyroxy acetophenone, in scientific microwave oven its transition metal complexes were from Ni(II), Mn(II), Cd(II), Fe(III), Cu(II), Zn(II), Co(II), Ag(I) salts. synthesized Schiff base ligand characterized elemental analysis, spectral technics such as UV-Visible, FT-IR, 1HNMR, LC-MS Thermo grav...

a series of new hexahydroquinoline and 1,4-dihydropyrimidine derivatives were synthesized. condensation of 2-methyl- thiazole-4-carboxaldehyde (1) with 1,3-cyclohexanedione and alkyl 3- aminocrotonate afforded 4-(2-methyl-thiazol-4-yl)-hexahydroquinoline while condensation of aldehyde (1) with benzoyl acetone and thiourea gave 1,4-dihydropyrimidine derivatives. the stereochemistry of 1,4-dihydr...

some n¬-acyl-n'-aryl thiourea derivatives 4(a-f) have been prepared by the reaction of acyl halides ammonium thiocyanate and aryl amines. the structures of synthesized compounds have been characterized by ir, 1hnmr spectral studies. the synthesized compounds 5(a-f) have been screened for antibacterial activity. the effect of the structure of the investigated compounds on the antibacterial activ...