Synthesis and structure elucidation of several series new hydrazones containing 1,2,4-triazine-5-one core their antioxidant activity are presented. The target compounds have been synthesized via interaction either 4-amino-6-( tert -butyl)-3-hydrazinyl-1,2,4-triazin-5(4 H )-one or 6-( -butyl)-3-hydrazinyl-1,2,4-triazin-5(2 with a wide range carbonyl group in moderate to high yields. Molecular st...

A family of ditopic hexadentate ligands based on the parent compound 2,6-bis(6-(pyrazol-1-yl)pyridin-2-yl)-1,5-dihydrobenzo[1,2-d:4,5-d’]diimidazole (L) was developed and synthesized by using a straightforward condensation reaction, which forms interlinking central benzo[1,2-d:4,5-d’]diimidazole bridge in ligand backbone. The two secondary amine groups benzodiimidazole unit tautomerize allow fo...

An efficient method for synthesis of cyclohexyl and cyclohexenyl α-amino acids via palladium-catalyzed three-component assemblies followed by ring-closing metathesis (RCM) is described. The present catalytic reaction is successfully extended to substituted benzylidene azlactones 2a-j RCH=(1,3-oxazole): R = alkyl or aryl. The amphiphilic bis-allylation of these substrates has been achieved by re...

The title Schiff base compound, C(13)H(16)N(3)O(+)·PF(6) (-), was derived from the condensation of 2-hydroxy-benaldehyde with the ionic liquid 1-(2-amino-ethyl)-3-methyl-imidazolium hexa-fluoro-phosphate in an ethanol solution. The asymmetric unit comprises one cation and two PF(6) (-) anions. The dihedral angle between the aromatic and imidazole rings is 15.2 (2)°. An intra-molecular O-H⋯N hyd...

Series of novel dichromophoric cyanine dyes based on 2-aminobenzothiazoles and 3-amino-1,2,4 -triazole have been synthesized in high yields. All the dyes have been classified as disperse dyes. Besides their electronic spectroscopic properties, high dye-uptakes on polyester, excellent fastness properties, highly extinction coefficients, and broad solvatochromic effects have been observed in thes...

The amino acid content in human hypophyseal growth hormone has been determined by chromatography on resin columns. On the basis of 29,000 for the molecular weight, the empirical formula of the hormone was obtained: lys(13)his(5)arg(14)asp(27) thr(14)ser(23)glu(34)pro(12)gly(13)ala(12)-(1/2 cys)(6)val(12)met(4)-ileu(10)leu(31)tyr(10)phe(15)try(1)(NH(3))(32).

all-endo-3-amino-5-hydroxybicyclo[2.2.2]octane-2-carboxylic acid (13) and all-endo-5-amino-6-(hydroxymethyl)bicyclo[2.2.2]octan-2-ol (10) were prepared via dihydro-1,3-oxazine or g-lactone intermediates by the stereoselective functionalization of an N-protected derivative of endo-3-aminobicyclo[2.2.2]oct-5-ene-2-carboxylic acid (2). Ring closure of b-amino ester 4 resulted in tricyclic pyrimidi...