We establish new classes of Ratliff-Rush closed ideals and some pathological behavior of the Ratliff-Rush closure. In particular, Ratliff-Rush closure does not behave well under passage modulo superficial elements, taking powers of ideals, associated primes, leading term ideals, and the minimal number of generators. In contrast, the reduction number of the Ratliff-Rush filtration behaves better...

Patients with advanced melanoma have a compromised anti-tumor immune response leading to tumor immune tolerance and a tumor microenvironment conducive to disease progression. Immunotherapy that successfully overcomes this tumor-mediated immune suppression has made the greatest impact in the management of this disease over the past few years. This progress through immunotherapy builds upon earli...

Recent advances in our understanding of the complex signaling pathways involved in immune system regulation, along with analyses of genetic differences between tumors and their normal cellular counterparts, have accelerated development of immune-based strategies for cancer treatment and prevention. More clinically relevant animal models have shown that successful immune-based strategies will re...

Standard-of-care chemo- or radio-therapy can induce, besides tumor cell death, also tumor cell senescence. While senescence is considered to be a principal barrier against tumorigenesis, senescent cells can survive in the organism for protracted periods of time and they can promote tumor development. Based on this emerging concept, we hypothesized that elimination of such potentially cancer-pro...

Pamela Bell, BS; Thelma Dangana, MBBS, MS; Galina Sidimirova, BSN; Robert A. Weinstein, MD, FIDSA, FSHEA; Louis Fogg, PhD; Michael Y. Lin, MD, MPH; Vincent B. Young, MD, PhD; Mary K. Hayden, MD and The CDC Prevention Epicenter Program; Internal Medicine/Infectious Diseases, University of Michigan, Ann Arbor, Michigan; Rush University Medical Center, Chicago, Illinois; Medical Laboratory Science...

BEST PRACTICE. For orthopedic specialists at Rush, good medicine and good teaching are inextricably linked. In this issue, 4 of our faculty discuss the many facets of orthopedic education at Rush—and why both teaching and learning are lifelong pursuits (see page 62). To view the 2016 Rush Orthopedics Journal online or to view past issues of the journal, please visit www.rush.edu/orthopedicsjour...

4. Fricton JR, Rindal DB, Rush WA, Flottemesch TJ, Durand EC, Thoele MJ, Huntley C, Godlevsky O, Enstad CJ, Rhodus, N (Abstract) Electronic Health Records to Improve Care of Patients with Medical Conditions. American Association of Dental Research Meeting, 2009. 5. Fricton JR, Rindal DB, Rush WA, Flottemesch TJ, Durand EC, Thoele MJ, Huntley C, Godlevsky O (Abstract). Electronic Health Records ...

Hymenoptera allergens are the main triggers for anaphylaxis in susceptible dogs and humans. venom specific immunotherapy (VIT), only disease-modifying treatment, has potential to prevent future life-threatening reactions human patients. Prospective clinical data on VIT efficacy currently lacking. Therefore, aim of this study was show that is not safe but also efficacious preventing allergic Hym...