Objective: a1-Adrenergic receptors (ARs) are known mediators of a positive inotropy in the heart, which may play even more important roles in heart disease. Due to a lack of sufficiently selective ligands, the contribution of each of the three a1-AR subtypes (a1A, a1B and a1D) to cardiac function is not clearly defined. In this study, we used a systemically expressing mouse model that overexpre...

An adaptive version of growing and pruning RBF neural network has been used to predict the system output and implement Linear Model-Based Predictive Controller (LMPC) and Non-linear Model-based Predictive Controller (NMPC) strategies. A radial-basis neural network with growing and pruning capabilities is introduced to carry out on-line model identification.An Unscented Kal...

The Adaptive Reuse (AR) of heritage buildings is a complex process, which aims to preserve the values while adapting them for use in present and transferring future. This paper identify steps this process develop structured model. model an ‘ideal’, it needs validation practice; however, expected that following can help conserve buildings. To come overview its main steps, literature review at in...

Objectives: The Avoidance-Endurance Fast-Screen (AEFS) is a 9-item self-report questionnaire that classifies patients with back pain into 4 activity-related subgroups, based on the Model of pain. objective this study was to translate AEFS Danish and investigate its discriminative abilities in large, diverse patient sample. Materials Methods: A total 851 specialist care-seeking severe chronic co...

We hypothesized that A2A adenosine receptor (A2A AR) activation causes vasorelaxation through cytochrome P-450 (CYP) epoxygenases and endothelium-derived hyperpolarizing factors, whereas lack of A2A AR activation promotes vasoconstriction through Cyp4a in the mouse aorta. Adenosine 5'-N-ethylcarboxamide (NECA; 10(-6) M), an adenosine analog, caused relaxation in wild-type A2A AR (A2A AR+/+; +33...

AA-LP Anti-aliasing lowpass AC3 Adaptive transform coder 3 ACR Absolute-category rating ADC Analog-to-digital converter ADPCM Adaptive differential pulse-code modulation AEC Acoustic echo cancellation / caneller AIR Acoustic impulse response ALP Adaptive lattice predictor ANC Active noise control or adaptive noise canceller AP Affine projection APC Adaptive predictive coding AR Auto-regressive ...

Background: ˝Radioadaptive Response˝ is well-documented phenomenon appeared in low dose ionizing radiation received in vitro and in vivo. Occupational exposure has always been a great concern for radiation workers therefore this study was performed to study radioadaptive response in terms of residual DNA double strand breaks as an endpoint in peripheral blood leukocytes of occupationally expose...

This study examined the effects of transfer of a 2.4-Mbp region of rat chromosome 1 (RNO1) from Brown Norway (BN) into fawn-hooded hypertensive (FHH) rats on autoregulation (AR) of cerebral blood flow (CBF) and the myogenic response of middle cerebral arteries (MCAs). AR of CBF was poor in FHH and FHH.1(BN) AR(-) congenic strains that excluded the critical 2.4-Mbp region. In contrast, AR was re...

The normal development and maintenance of the prostate is dependent on androgen acting through the androgen receptor (AR). AR remains important in the development and progression of prostate cancer. AR expression is maintained throughout prostate cancer progression, and the majority of androgen-independent or hormone refractory prostate cancers express AR. Mutation of AR, especially mutations t...