BACKGROUND At M phase, cyclin B1 is phosphorylated in the cytoplasmic retention sequence (CRS), which is required for nuclear export. During interphase, cyclin B1 shuttles between the nucleus and the cytoplasm because constitutive nuclear import is counteracted by rapid nuclear export. In M phase, cyclin B moves rapidly into the nucleus coincident with its phosphorylation, an overall movement t...

THE TITLE COMPOUND [SYSTEMATIC NAME: (12R)-4,8-dimethyl-12-[(1'R)-1',2',3',4'-tetrahydro-1'-naphthyl)aminomethyl]-3,14-dioxatricyclo[9.3.0.0(2,4)]tetradec-7-en-13-one}, C(25)H(33)NO(3), was formed from the reaction of (1R)-1-amino-tetra-lin with parthenolide in methano-lic solution. X-ray crystal structure analysis determined that the configuration of the new chiral center in the title compound...

Importin13 (Imp13) is a bidirectional karyopherin that can mediate both import and export of cargoes. Imp13 recognizes several import cargoes, which include the exon junction complex components Mago-Y14 and the E2 SUMO-conjugating enzyme Ubc9, and one known export cargo, the translation initiation factor 1A (eIF1A). To understand how Imp13 can perform double duty, we determined the 3.6-Å crysta...

Hyaluronan is synthesized within the cytoplasm and exported into the extracellular matrix through the cell membrane of fibroblasts by the MRP5 transporter. In order to meet the law of electroneutrality, a cation is required to neutralize the emerging negative hyaluronan charges. As we previously observed an inhibiting of hyaluronan export by inhibitors of K(+) channels, hyaluronan export was no...

Assuming preferences to be generated by an aggregate utility function, an aggregate demand function for imports and exports is defined as a function of import and export prices and the deficit in the balance of payments on current account, in a model with nontradable as well as traded goods. It is shown that this function is integrable, hence can be generated by maximizing a utility function (w...

This research aims to examine the effect of export and import on economic growth. The data used are time series consisting export, in period 2004Q1-2018Q1. test results using autoregressive distributed lag (ARDL) model indicates that short long run, there is In every 1% decline lead 1.17% increase growth, while 1.83% growth.Keywords: Export, import, ARDL modelJEL Classifications: C130, F140, F4...

Due to the special requirements of distributed systems, it is important that modeling techniques for this kind of systems ooer a stringent module concept. Each module has to support the encapsulation of data structure as well as functionality also at runtime. Modular graph transformation, presented in this contribution, supports these features. Modules are built up of speciications where attrib...

BACKGROUND Proteins generally enter or exit the nucleus as cargo of one of a small family of import and export receptors. These receptors bear distant homology to importin beta, a subunit of the receptor for proteins with classical nuclear localisation sequences (NLSs). To understand the mechanism of nuclear transport, the next question involves identifying the nuclear pore proteins that intera...

This paper analyses the reasons of the export growth for the Shandong agricultural products which can be attributed to the Shandong agricultural export enterprises’ efforts and Shandong provincial government’s strong supports. Though Shandong agricultural products exports achieved a big success all over the China, there are still some internal problems and external constraints that hinder its f...