The strawberries and their phytochemicals are beneficial during cancer, infections, obesity, neurological and cardiovascular diseases (CVD). The present study explores the effect of freeze dried strawberry powder (FSP) on alloxan induced hyperlipidemia in albino rats. Alloxan (150mg/ kg bw) induced diabetic animals treated with FSP (700 mg/kg bw for 45 days) were analyzed for serum lipid profil...

BACKGROUND Diabetes mellitus has remained a significant contributor to morbidities and mortalities in our environment despite all efforts to curb the trend. Regrettably, conventional, orthodox hypoglycemic agents have remained unaffordable. Consequently the need for available and affordable alternatives cannot be overemphasized. OBJECTIVES To determine the effect of the methanolic seed extrac...

The antidiabetic activity of aqueous, ethanolic and hexanic extracts of Bauhinia forficata was investigated in a model of alloxan-induced diabetes in rats. The biochemical parameters studied were: plasma glucose, serum triglycerides, cholesterol, high density lipoprotein (HDL), and low density lipoprotein (LDL). Extracts were administered daily for 7 d at doses of 200 and 400 mg/kg, p.o., 48 h ...

The hypoglycemic effects of the fruit extract of C. metuliferus was investigated in normoglycemic and alloxan-induced hyperglycemic rats. The results showed that there was an insignificant (P > 0.05) decrease in the blood glucose concentration of normoglycemic rats treated with oral doses of 1000 and 1500 mg/kg of the extract. On the other hand, 500 mg/kg of the fruit extract produced an insign...

AIM To determine whether treatment with the stem cell stimulator Olimpiq® Stem×Cell prevents increase of retinal and renal vascular permeability in alloxan-induced diabetic rats. MATERIALS AND METHODS Two groups of Wistar rats were made diabetic by single intraperitoneal injection of Alloxan. The third, the control group, received vehicle alone. One diabetic group received Olimpiq® Stem×Cell ...

The use of the paired epididymal fat pads of the rat under carefully controlled conditions has revealed the marked sensitivity of this tissue to insulin in vitro or in viva (l-3) and has permitted the demonstration of numerous abnormalities in the metabolism of adipose tissue from alloxan diabetic rats (4, 5). It has been shown that insulin in vitro or in vivo rapidly increases the depressed ox...

Invivo Antidiabetic evaluation of Neem leaf extract in alloxan induced ratsShravan Kumar Dholi, Ramakrishna Raparla, Santhosh Mankala, Kannappan Nagappan

objectives: turnip leaf has been used in folk medicine of iran for the treatment of diabetes. however,so far no scientific study has been done to support its use in traditional medicine. the present study was carried out to evaluate the possible hypoglycemic efficacy of aqueous extract of turnip leaf (aetl) in diabetic rats. materials and methods: alloxan-induced diabetic rats were orally treat...

the hypoglycemic effect of ethanolic extract of casearia esculenta was investigated on alloxan induced diabetic rats. the blood glucose levels were measured at 0, 1, 2 and 3 h after the treatment. the ethanolic extract of c. esculenta (250 mg/kg) reduced the blood glucose of normal rat from 85.50±1.22 to 64.67±3.27 mg/dl, 3 h after oral administration of the extract (p<0.05). it also significan...

The herbal formulation, DRF/AY/5001, elicits hypoglycemic/antidiabetic effects in both normal and experimentally induced hyperglycemic (epinephrine and alloxan) rats. Further, herbal formulation treatment can significantly alter the pattern of glucose tolerance in normal and diabetic rats. It is possible that the herbal formulation may act through both, pancreatic and extra-pancreatic mechanism...