Employing more than one supplier and splitting orders between them is a strategy employed in supply chains to lessen the lead-time risk in unstable environments. In this paper we present a multiple-sourcing inventory system with stochastic lead-times and constant demand controlled by a continuous review, reorder point-order quantity inventory policy. We consider the situation in which the order...

In a procurement setting, this paper examines agreements between a buyer and one of the suppliers which would increase their joint surplus. The provisions of such agreements depend on the buyer’s ability to design the rules of the final procurement auction. When the buyer has no such ability, their joint surplus can be increased by an agreement which grants to the preferred supplier a right-of-...

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acute lymphoblastic leukemia (all) is one of the most prevalent hematologic malignancies in children. although the cure rate of all has improved over the past decades, the most important reason for all treatment failure is multidrug resistance (mdr) phenomenon. the current study aims to explain the mechanisms involved in multidrug resistance of childhood all, and introduces atp-binding cassette...

Vendor performance plays a key role in price, quality, timely delivery and service in achieving the goals of the supply chain. Given this, today's supplier performance has become a critical element in the success or failure of a company. In this study, an idealized planning model with multi-criteria decision-making approach with network analysis tool based on the expansion of fuzzy quality func...

Understanding muscle energetics is a problem in optimizing supply of ATP to the demands of ATPases. The complexity of reactions and their fluxes to achieve this balance is greatly reduced by recognizing constraints imposed by the integration of common metabolites at fixed stoichiometry among modular units. ATPase is driven externally. Oxidative phosphorylation and glycogenolysis are the supplie...

This paper proposes and investigates a theoretical model in continuous time to analyze the real switching options that an economic entity in relationships with multiple external economic agents holds and the corresponding implications for equilibria between the entity and the agents if they are active. Although our basic model is generally applicable in several widely different economic scenari...