Block copolymer nano-micelles are especially important in cancer treatment because of their fine dimensions. In this article, three systems of amphiphilic copolymers with similar lengths and different ratios of the hydrophobic and hydrophilic chains are studied using implicit-solvent coarse-grained molecular dynamics simulations. The factor fphil is defined as the ratio of the number...

In this paper, we use a combination of Legendre and Block-Pulse functionson the interval [0; 1] to solve the nonlinear integral equation of the second kind.The nonlinear part of the integral equation is approximated by Hybrid Legen-dre Block-Pulse functions, and the nonlinear integral equation is reduced to asystem of nonlinear equations. We give some numerical examples. To showapplicability of...

Background: Potassium, as an extracellular ion, plays an important role in the electrophysiologic function of the myocardium and any change in extracellular concentration of this ion might have a marked impression upon myocyte electrophysiologic gain. High serum potassium levels are thought to impair pulse conduction in Purkinje fibers and ventricles more than that in the Atrio...