Adding a small amount of an immiscible fluid to a particle suspension can lead to particle bridging and network formation. This effect occurs both if the secondary fluid wets the particles better or worse than the bulk fluid. The capillary bridging phenomenon can be used to stabilize particle suspensions and precisely tune their rheological properties. This allows stable food products to be cre...

The means by which extracellular matrix density regulates three-dimensional capillary morphogenesis is unclear. To study this phenomenon, we utilized a fibrin-based in vitro assay in which a fibroblast monolayer is plated atop a fibrin gel approximately 2.5 mm away from endothelial cell-coated beads within the matrix. Increasing fibrin density from 2.5 to 10 mg/ml resulted in a threefold reduct...

PURPOSE Retinal vascular networks are observed as a layered structure residing in a nerve fiber layer and an inner nuclear layer of the retina. This study aimed to evaluate reflectance confocal adaptive optics scanning laser ophthalmoscopy (AO-SLO) for imaging of the layered retinal vascular networks. METHODS This study included 16 eyes of 16 healthy cases. On the fovea, 2.8- and 3.0 mm2-area...

OBJECTIVE Estrogen replacement therapy (ERT) ameliorates symptoms in postmenopausal women with syndrome X. We hypothesized that estrogen deprivation and replacement may modulate coronary expressions of angiogenic molecules, thereby modifying the coronary capillary network in perimenopausal women. METHODS AND RESULTS Middle-aged (40-week-old) female rats were subjected to sham surgery, ovariec...

The intra-voxel incoherent motion (IVIM) model assumes that blood flowing in isotropically distributed capillary segments induces a phase dispersion of the MR signal, which increases the signal attenuation in diffusion-weighted images. However, in most tissue types the capillary network has an anisotropic micro-architecture. In this study, we investigated the possibility to indirectly infer the...

OBJECTIVES This article aims to determine the effect of acute pancreatitis on microvascular morphology and the impact of treatment with hyperbaric oxygen (HBO). METHODS Sixty-seven male Wistar rats were induced with acute pancreatitis by retrograde bile duct injection. Rats were randomized to 12-hourly HBO or control treatment. Two rats in each group were killed at baseline and 24, 48, and 72...

Gastric liposarcoma is very rare such that only a few cases have been reported to date. We present a case of a 62 - year - old diabetic man who presented with epigastric pain, vomiting, constipation and melena. The physical examination was unremarkable. By computed tomography (CT), a large mass with low attenuation value was seen in the left abdominal cavity. Histologic examination of a ga...

objective(s): previous studies showed that skeletal muscle microcirculation was reduced in chronic heart failure. the aim of this study was to investigate the effects of endurance training on capillary and arteriolar density of fast and slow twitch muscles in rats with chronic heart failure. materials and methods: four weeks after surgeries (left anterior descending (lad) artery occlusion), chr...

In striated muscle, the number of capillaries containing moving red blood cells increases with increasing metabolic demand. This phenomenon, termed capillary recruitment, has long been recognized but its mechanism has been unclear. Here, a theoretical model for metabolic blood flow regulation in a heterogeneous network is used to test the hypothesis that capillary recruitment occurs as a result...