introduction: metastatic lesions of the oral cavity are extremely rare, accounting for approximately 1% of all malignant oral tumors. the most common primary sources of metastatic tumors in the oral region are, from the most to the least common, the breast, lung, kidney, bone, and colon. renal cell carcinoma accounts for nearly 3% of all adult malignancies. it usually metastasizes to the lungs,...

background: esophageal carcinoma is one of the most lethal gastrointestinal (gi) malignant tumors worldwide.  the disease is known to have a high incidence in northern iran; however, its condition in the south is not much clear.   objective: in this retrospective study we investigated the epidemiology and time trends of esophageal carcinoma in fars province, south of iran.   methods : in a retr...

pure apocrine carcinoma of the breast is one of the rare variants of invasive breast carcinoma. significant research has been conducted on cases of apocrine carcinoma, and the results may help in development of new therapies and assessing prognosis. we hereby present a case of pure invasive apocrine carcinoma in a 50-year old female, with a short review of recent developments with regard to thi...

radioiodine (1-131) is the treatment of choice in differentiated thyroid carcinoma. external radiotlierapy however, has it's own roie in these tumors. treatment of anaplastic thyroid carcinoma 1ms not acliieved any notahle success yet, though combined - modality regimens of radiotherapy and chemotherapy have sometimes shown significant results. in this paper the role of radiotlierapy and chemot...

Background & Objective: Some prostatic lesions contain small suspicious foci for prostatic carcinoma in which the morphological features are equivocal. Two immunohistochemical markers namely, cytokeratin 34 beta E12 (Ck34βE12) and α-Methylacyl-CoA racemase (AMACR), were evaluated in these lesions for a definitive diagnosis and avoiding misdiagnosis or overdiagnosis of prostatic...

Introduction:  Carcinoma of the larynx is an extremely uncommon clinical entity in pediatric age. The diagnosis of the laryngeal carcinoma is often delayed due to the low index of suspicion. The factors contributing to delayed diagnosis include the similarity of its symptoms to common benign lesions of the larynx in childhood and difficult examination of the larynx in pediatric patients. ...

adrenocortical carcinoma (acc) is a rare tumor and usually a fatal disease which can develop at any age in either sex. differential diagnosis between malignant and benign adrenal mass is not easy which leads to significant clinical challenge for optimal treatment. here we report a 22-year-old woman diagnosed with primary hyper aldostronism initially but disease relapsed during six months and ma...

context several risk factors play the role in the development of hepatocellular carcinoma (hcc) from which chronic hepatitis b and c infections are the most important ones. dna integration of hepatitis viruses alters the function of critical genes promoting malignant transformation of virus-infected liver cells. evidence acquisition there are remarkable geographic differences in prevalence of c...

conclusions pivka-ii was as efficient as afp when used as a single marker for hcc screening and the combination of two biomarkers gave a better performance. results the sensitivity and specificity of pivka-ii were 74.6% and 67.8% at a cutoff of 40 mau/ml and 64.2% and 89.7% at a cutoff of 200 mau/ml. the sensitivity and specificity of afp were 76.7% and 65.0% at a cutoff of 20 ng/ml and 60.4% a...