Introduction: The stress-oxidative is involved in doxorubicin (DOX)-induced cardiotoxicity. Due to the potential and previous reported for antioxidant properties of atorvastatin, omega-3, vitamin E and vitamin C, their efficacy to prevention of DOX-induced cardiotoxicity was investigated in this study. Methods: Fifty-six male rats were divided into 8 groups which received omega-3, atorvastati...

objective(s):the use of doxorubicin (dox) is limited by its dose-dependent cardio toxicity in which reactive oxygen species (ros) play an important role in the pathological process. the aim of this study was to evaluate the protective effect of three medicinal plants, nigella sativa (n), glycyrrhiza glabra (g) and zingiber officinale (z), and their combination (ngz), against dox-induced apoptos...

1 Master of Public Health, Master of Health Administration, Hepatology Section, Department of Internal Medicine, Fundación Cardio-Infantil, Bogotá, Colombia. 2 Second Year Resident, Department of Internal Medicine, Universidad del Rosario, Fundación Cardio-Infantil, Bogotá, Colombia. 3 Internist, Gastro-hepatologist in the Hepatology Section of the Department of Internal Medicine, Fundación Car...

Dear colleagues, It is my pleasure to welcome you in the third issue of Journal of Cardio-Thoracic Medicine and I hope you find it interesting. In this issue, beside the valuable original articles and an interesting case report, a useful review article have been published concerning the role of nuclear medicine in the management of solitary pulmonary nodule.I am proud to announce you that Journ...

the lipid accumulation product is a novel, safe and inexpensive index of central lipid over accumulation based on waist circumference and fasting concentration of circulating triglycerides. this study was designed to investigate the ability of lipid accumulation product to predict cardio-metabolic risk factors in postmenopausal women. in this cross-sectional study, 264 postmenopausal women by u...

back ground and purpose: air pollution in cities thorough the world, is a complex mixture of poisonous compounds which are always combustion products particulate matters (pm) are instant member of this mixture. despite wide spectrum health effects of pm, effects on death seem to be the most important one. the main purpose of this study was to estimate number of cardio pulmonary death in adults ...

Silymarin ‘milk thistle’ (Silybum marianum) plant, has been used for years treatment of different diseases such as liver and gallbladder disorders, protecting against snake bite insect stings, mushroom poisoning alcohol abuse. antioxidant, anti-lipid peroxidative, antifibrotic, anti-inflammatory, immunomodulatory, regeneration activities. The cardioprotective activities silymarin were primarily...