10.2217/14750708.5.2.203 © 2 Parkinson’s disease is a neurodegenerative disorder manifested by a combination of motor and non-motor symptoms. Levodopa, a dopamine precursor, is the most efficacious drug available to control the symptoms of Parkinson’s disease. Almost all other medications with symptomatic benefit for Parkinson’s disease show their effect by facilitating the dopaminergic system,...

The article is devoted to the study of association genotypes genes monoamine oxidase A (MAOA) and catechol-O-methyltransferase (COMT) with emotional intelligence personality traits young people, such as extraversion-introversion, empathy, alexithymia. work was attended by students-psychologists, in amount 100 people. following methods were used: Test (D.V. Lyusin); Emotional Empathy Questionnai...

Protection against anaphylactic shock in mice by reserpine has been shown to be a delayed phenomenon, probably not dependent upon a direct effect of reserpine. The release and depletion of catechol amines by reserpine show little likelihood of being responsible for protection because these substances are in themselves protective against anaphylactic shock, while beta-TM 10, a drug which interfe...

Infusions of 2.5-7.8 ng. noradrenaline/Kg./min. over 30 min. and intruperitonenl injections of noradrenaline and adrenaline up to 2000 Mg/Kg. in the cat had no effect on the catechol amine content of the. heart, spleen, liver, kidney and skeletal muscle, except for a slight increase in the adrenaline content. It is concluded that these organs lack the ability to accumulate i-iirulating catechol...

A series of copper(ii) complexes, viz. [Tp(MeMe)Cu(Cl)(H2O)] (), [Tp(MeMe)Cu(OAc)(H2O)] (), [Tp(MeMe)Cu(NO3)] () and [Tp(MeMe)Cu(ClO4)] () containing tris(3,5-dimethylpyrazolyl)borate (KTp(MeMe)), have been synthesized and fully characterized. The substitution reaction of with thiourea was studied under pseudo-first-order conditions as a function of concentration, temperature and pressure in me...

The chemical laboratory measures used in the diagnosis of pheochromocytoma have been evaluated. Bio-assay, fluorometric, and spectrophotometric methods were used. Urinary VMA and catechol amine values found for normal and hypertensive groups compared well with those reported by other investigators. The quantitative measurement of urinary VMA by means of a proposed ethyl acetate extraction prove...

Infusions of 2.5-7.8 ng. noradrenaline/Kg./min. over 30 min. and intruperitonenl injections of noradrenaline and adrenaline up to 2000 Mg/Kg. in the cat had no effect on the catechol amine content of the. heart, spleen, liver, kidney and skeletal muscle, except for a slight increase in the adrenaline content. It is concluded that these organs lack the ability to accumulate i-iirulating catechol...

Reaction thermodynamics and potential energy surfaces are calculated using density functional methods to investigate possible reactive Cu/O(2) species for H-atom abstraction in peptidylglycine alpha-hydroxylating monooxygenase (PHM), which has a noncoupled binuclear Cu active site. Two possible mononuclear Cu/O(2) species have been evaluated, the 2-electron reduced Cu(II)(M)-OOH intermediate an...

Infusions of 2.5-7.8 ng. noradrenaline/Kg./min. over 30 min. and intruperitonenl injections of noradrenaline and adrenaline up to 2000 Mg/Kg. in the cat had no effect on the catechol amine content of the. heart, spleen, liver, kidney and skeletal muscle, except for a slight increase in the adrenaline content. It is concluded that these organs lack the ability to accumulate i-iirulating catechol...