the objectives of this work was to examine the toxicological effect and molecular changes caused by a heavy metal pollutant mercuric chloride (hgcl2), in fresh water snakehead channa punctatus, locally known as taki fish in bangladesh. when fishes were exposed to hgcl2, it induced death of the fishes in a concentration-dependent manner. 1 mm, the highest concentration tested in this study, was ...

Hyperthermia has been shown to have promising antitumor effects for various types of malignant tumors. It is one the most potent adjuvant cancer therapy when combined with radiotherapy and chemotherapy. The range hyperthermia temperature (40-45 ℃) induces cell killing depending on period treatment. Although kinetics inactivation by heat using clonogenic assay well studied, molecular mechanism h...

isolated rat hepatocytes in culture were incubated with different concentrations of iron-sorbitol (50, 100, 150, and 200 µm) to assess the changes in reactive oxygen species (ros) and lipid peroxidation leading to apoptotic hepatocyte cell death. the viability of hepatocytes was declined depending on the iron concentration. one hour incubation of the cells with 100 µm iron resulted in decreased...