[Purpose] The purpose of this study was to investigate the impact on rat knee joints of extracorporeal shock wave therapy after experimentally induced intracerebral hemorrhage. [Subjects and Methods] Sprague-Dawley (SD) rats were divided into an experimental group that received extracorporeal shock wave therapy after central nervous system injury (n=10) and a control group that did not receive ...

the incidence of traumatic brain injury (tbi) are annually increasing, developed tissue engineering methods could represent the definite remedies for patients with strongly injured central nervous system and have a great effect in the public healthcare cost. the current clinical treatments in tbi display several limitations. furthermore, several therapies, coming from neural tissue engineering ...

background:modafinil, a non-amphetamine central nervous system stimulant, is a wakefulness-promoting agent indicated for use in shift work sleep disorder, narcolepsy, and obstructive sleep apnea. the trend in modafinil overexposure over a ten-year period and the population likely to experience a resulting clinical effect is evaluated. methods: using data from the american association of poison ...

since its first description of botulism toxicity in 1820s, specific formulations of botulinum neurotoxin (bont) have been introduced with different clinical benefits. however, there is increasing number of adverse events reported to food and drug administration. this report presents the case of 62-year-old woman with parkinson’s disease who received bont injections to treat painful spasticity i...

spinal cord injury (sci) results in the damage of motor and sensory pathways. the molecular and cellular structure of the injury milieu has been shown to be vital for endogenous regeneration in most tissues. regeneration of injured central nervous system (cns) is limited by damaged cell environment. biomaterial scaffolds can reconstruct injured cns tissue following sci by promoting the migratio...