BACKGROUND AND PURPOSE MR imaging is the method of choice for pediatric neuroimaging. Sedation is often needed to suppress patient motion and ensure diagnostic image quality, and propofol is rapidly becoming the preferred anesthetic. The purpose of this study was to document a new finding on fast fluid-attenuated inversion recovery (fast-FLAIR) MR images of children anesthetized with propofol t...

Domkie, a Mahomedan grooin, aged about 25 years, was admitted into the second physician's ward, Campbell hospital, with symptoms of acute idiopathic tetanus, on the 6th January 1876, the attack having been brought on by exposure to cold about 3 or 4 days previously. All the symptoms of the disease were present; there was marked opisthotonos, and the fits were strong, occurring at short interval...

At the time of his admission he had spasms about every ten minutes, and cculd swallow nothing but fluids, although able to open his mouth enough to admit an ordinary spoon. Pulse 90; temperature in armpit 105?. Bowels had been costive for several days, until the day before admission. At 8-30 a.m. given 20 grs. chloral hydrate. Slept for some hours, and had no spasms during sleep. 5 p.m., anothe...

OBJECTIVE The purpose of this study was to compare efficacy and safety of oral chloral hydrate (CH) and promethazine (PZ) for sedation during electroencephalography (EEG) in children. METHODS In a parallel single-blinded randomized clinical trial, sixty 1-10 year old children referred to EEG Unit of Shahid Sadoughi Hospital from January 2010 to February 2011 in Yazd, Iran, were evaluated. The...

The purpose of this study were to determine the association of scores on the North Carolina Behavior Rating Scale (NCBRS) to those of the Frankl scale during restorative visits; and to quantify and compare rated behavior of children during an oral examination and restorative visits involving either a placebo or a combination of chloral hydrate (CH) and hydroxyzine. Fifteen patients 21-37 months...

Meywa Sing, a sowar in the Xlth Bengal Lancers, while preparing to go on guard on the evening of the 21st April suddenly complained of a pain commencing in his right foot and running up the inside of his leg ; he then fell down in an insensible state, and was taken to hospital; on the morning of the 22nd, he had a similar attack to the above, which was without doubt epileptic, the aura being mo...

It was said by a great master, Samuel Taylor Coleridge, that every thinking and working man should take stock now and then of his intellectual material, test its force and action, and satisfy himself that it still has practical meaning and power. Those busy craftsmen, physicians and surgeons, ought to take earnest heed of Coleridge's saying. Things in use yesterday go out of fashion to-day, alt...

UNLABELLED Chloral Hydrate (CH) is a sedative and hypnotic drug used in pediatric procedures owing to the low depressive effect it has on the respiratory and cardiac systems. AIM To assess the efficacy of the drug in performing ABR and to systematize its use. MATERIALS AND METHODS A prospective cross-sectional study with 41 children without history of heart or lung disease. The initial dose...

Brow, a tall, strong, muscular man, of the cultivator caste, about 36 years of age, was admitted into the dispensary with, tetanus, which was said to have commenced four days previ? ously without apparent cause; there was no history of any wound or hurt, or of exposure to cold or wet. His state on admission was as follows :?Muscles of neck and jaw were quite rigid, so that he could not open his...

Chloral hydrate has been found in our drinking water supplies at levels up to 5 micrograms/1. The purpose of this study was to evalute the acute and subchronic toxicology of chloral hydrate in the random-bred CD-1 mouse, to provide data for risk assessment. The acute oral LD50 of this compound was 1442 and 1265 mg/kg in male and female mice, respectively. Acute toxicity appeared to be related t...