Ailanthus excelsa (Stem bark) are used in folk medicine for a treatment of inflammation, arthritis, expectorant, stimulant and asthma. Acute toxicity study of A. excelsa stem bark was performed on mice (Swiss) and albino rats (Wistar strain),given single doses 1,10, 50, 100 ,1000 and 2000mg/kg,po. showed normal behavior and no mortality up to 14 days except 500,1000 and 2000mg/kg dose 20%, 60.0...

In this study we used several models for evaluation of probable anti-inflammatory and antinociceptive effects of the flavonoid fraction of the leaves of Voacanga africana, using mice and rats. The extract (50 150mg/kg, p.o) inhibited, in a dose-related manner, carrageenan induced paw oedema in rats. The extract caused a significant inhibition of the cotton-pellet granuloma. Vascular permeabilit...

Urtica atrichocaulis, an endemic plant to China, is commonly used to treat rheumatoid arthritis even though its pharmaceutical activities and chemical constituents were not studied. Herein, we reported our investigations on the chemical compositions of the phenolic compounds-rich fraction from U. atrichocaulis (TFUA) and their antirheumatoid arthritis activities. We found that the TFUA signific...

Anti-inflammatory, antiarthritic and analgesic effect of a herbal product (DRF/AY/4012) was evaluated in animal models. Herbal product treatment induced a dose dependent anti-inflammatory activity in acute inflammatory models (carrageenin and egg-albumin induced rat hind paw edema). It also elicited promising anti-inflammatory activity in chronic inflammatory models (cotton pellet granuloma and...

Joshanda, a polyherbal product is commonly used to treat inflammation of the mucous membranes of nose and air passages. The current study was planned to evaluate the antiinflammatory and antioxidant activity of Decoction of Joshanda (DJ). DJ was challenged in carrageenan induced paw edema and cotton pellets induced granuloma at 100, 200 and 300 mg/kg i.p. for its antiinflammtory profile. Howeve...

Objective: To explore the anti-inflammatory activity of calcium channel blockers. Material and Methods: The anti-inflammatory activity was determined by producing inflammation in rats of either sex. Acute inflammation was produced by injecting carrageenan, formalin and histamine in hindpaw of rats. For sub-acute inflammation the cotton pellets granuloma method was employed. Formaldehyde induced...

AIM The aim was to test whether the ethanolic extract of Fumaria indica (FI) possesses anti-inflammatory and analgesic activities, and fumaric acid (FA) could be one of its bioactive constituent involved in such activities of the extract. MATERIALS AND METHODS For anti-inflammatory activity, carrageenan-induced edema and cotton pellet induced granuloma tests in rats and for analgesic activity...

INTRODUCTION Murdannia loriformis (hassk) Rolla Roa et Kammathy, family Commelinaceae, is used by Chinese practitioners as a remedy for cancer in an early stage, and also for treating other diseases including colds, throat infections, pneumonia, diabetes mellitus, flu and inflammation. Although anticancer as well as other pharmacological effects of M. loriformis have been reported, its anti-inf...

Background and Aims: The current study was conducted to compare the expression levels of collagen type Π and X during chondrogenesis of human adipose-derived mesenchymal stem cells (hADMSCs) pellet and micromass cultures.  Materials and Methods: Extracted hADMSCs were cultured until three passages and then transferred to pellet and micromass cultures in the experimental groups of day 7 and day...

Traditionally aerial parts of Barleria prionitis Linn. has been used in the inflammation, fever & toothache. The present study was undertaken to evaluate the anti-inflammatory and anti-nociceptive activity of 50% ethanolic extract of the flower of B. prionitis (BPF) in experimental animals. The BPF in doses of 50, 100 and 200 mg/kg caused a dose-dependent inhibition of swelling caused by carrag...