To determine which preconditioning and pretensioning techniques should be applied to soft tissue grafts during anterior cruciate ligament (ACL) reconstruction to avoid loss of tension after surgery, fresh semitendinosus and tibialis anterior tendons underwent tensile mechanical testing with 4 pretensioning and/or preconditioning techniques. A mechanical tester was used to collect the data. Grou...

In this paper, we implement the combined method of drilling stop hole and FRP reinforcement to repair cracked steel plates subjected cyclic tension. The crack initiation growth are experimentally investigated. stress distribution at residual fatigue life evaluated by FEM. effects on prolonging analyzed. results show that effectiveness only using is limited, while has dramatically prolonged life...

Abstract The work presents the results of an experimental study mechanical behavior polymer composite materials (PCM) subjected to sequential cyclic and quasi-static loads at normal temperatures. methodological features testing composites under complex influences are considered. tests for preliminary subsequent tension fiberglass specimens with different layouts given in fatigue sensitivity’s d...

Abstract Under strong earthquakes, reinforced concrete (RC) walls in high-rise buildings, particularly wall piers that form part of a coupled or core system, may experience axial tension–flexure loading. In this study, detailed finite element model was developed VecTor2 to provide an effective tool for the further investigation seismic behaviour RC subjected tension and cyclic lateral The verif...

Ductile fiber-reinforced cement-based composites (DFRCCs) are being investigated for new design as well as retrofitting of structures in seismic regions. DFRCC is highly ductile and is characterized by strain-hardening in tension to strains over 3% and by unique cyclic loading behavior. To accurately predict the structural performance of DFRCC components under cyclic and seismic loading, a robu...

Intestinal segments obtained from guinea pig ileum were set up in an organ bath to record peristaltic responses to distension by a pressure rise in the lumen. The effects of drugs applied in the bathing medium on the peristaltic responses were examined. Sodium nitroprusside (10(-9) M to 10(-5) M) stimulated the peristaltic reflex. Nitroglycerin (10(-7) M) was similarly effective in stimulating ...

Hypertrophic scars (HTS), the excessive deposition of scar tissue by fibroblasts, is one of the most common skin disorders. Fibroblasts derived from surgical scar tissue produce high levels of α-smooth muscle actin (α-SMA) and transforming growth factor-β1 (TGF-β1). However, the molecular mechanisms for this phenomenon is poorly understood. Thus, the purpose of this study was to evaluate the mo...

In lung fibrosis tissue architecture and function is severely hampered by myofibroblasts due to excessive deposition of extracellular matrix and tissue contraction. Myofibroblasts differentiate from fibroblasts under the influence of transforming growth factor (TGF) β(1) but this process is also controlled mechanically by cytoskeletal tension. In healthy lungs, the cytoskeleton of fibroblasts i...

a framework for development of constitutive models including damage progress, based on semi-micromechanical aspects of plasticity is proposed for concrete. the model uses sub-loading surface with multilaminate framework to provide kinematics and isotropic hardening/softening in the ascending/descending branches of loading and can be able to keep stress/stain paths histories for each plane separ...

The effects of (-)-isoproterenol covalently linked to glass beads on inotropic state, cyclic AMP concentration, and phosphorylase b to a conversion was studied in cat and guinea pig papillary muscles. Biochemical responses also were measured in mouse diaphragm sections. In cat papillary muscles under normal conditions and in guinea pig muscles partly depolarized with 22 mM K+ an increased inotr...