Sedation in children is increasingly emerging as a minimally invasive technique that may be associated with local anaesthesia or diagnostic and therapeutic procedures which do not necessarily require general anaesthesia. Standard monitoring requirements are not sufficient to ensure an effective control of pulmonary ventilation and deep sedation. Capnography in pediatric sedation assesses the ef...

Background: Some patients with respiratory failure who are in need of mechanical ventilation require sedation to tolerate the inserted endotracheal tube (ETT) and other unpleasant stimuli. While a light sedation is satisfactory, deep sedation can interfere with the weaning process of patient from mechanical ventilator. Nevertheless, so far, the ideal regimen for sedatives and analgesics has not...

BACKGROUND We compared the accuracy and practicability of a new combined ear sensor device measuring pulse oximetry and transcutaneous carbon dioxide tension. METHODS Validation studies were done by comparing the results of the combined sensor with arterial blood gas measurements. In an observational part, monitoring data were obtained from 25 patients undergoing colonoscopy, sedated with mid...

BACKGROUND Deep sedation or general anesthesia is generally used during atrial fibrillation (AF) ablation. The aim of this study was to report the safety and feasibility of minimal sedation during AF ablation. METHODS AND RESULTS One thousand and fifty-two AF ablation procedures in 819 patients (62 ± 11 years, 621 men, 506 paroxysmal) were included. Boluses of intravenous hydroxyzine pamoate ...

Molybdenum cofactor (MC) deficiency is defined as a progressive neurodegenerative and neurometabolic disease, characterized by convulsions, severe mental and motor retardation resistant to the treatment. Patients with MC deficiency usually need at least sedation for even minor interventions such as dental examination or treatment. Sedation or general anesthesia for these patients may be complic...

During gastrointestinal endoscopy, patients may reach a level of sedation that is deeper (i.e. deep sedation) than intended to be (i.e. moderate sedation). In such cases the ability to restore respiratory and cardiovascular function is critical. Supportive measures should be combined with administration of specific pharmacologic antagonists in cases of imminent ventilatory failure. Naloxone rap...

background: some patients with respiratory failure who are in need of mechanical ventilation require sedation to tolerate the inserted endotracheal tube (ett) and other unpleasant stimuli. while a l ight sedation is satisfactory, deep sedation can interfere with the weaning process of patient from mechanical ventilator. nevertheless, so far, the ideal regimen for sedatives and analgesics has no...