Gel permeation chromatography was used to fractionate zinc-bound constituents in haemolysates of human blood samples. The zinc content of the fractions was determined by electrothermal atomic absorption spectrometry. The zinc-containing enzyme, carbonic anhydrase, was identified by isoelectric focusing. A fraction of more than 0.9 of the zinc eluted from the column was bound to the carbonic anh...

BACKGROUND Celiac disease (CD) is an immunologic enteropathy triggered by the intake of gluten. It is thought that the enteropathy impairs gut function and absorption. OBJECTIVE We assessed the zinc-absorption capacity and small-bowel integrity in children with CD. DESIGN Children in whom a diagnosis of CD was considered clinically and either confirmed (n = 16; Marsh score ≥3) or not (n = 2...

BACKGROUND Zinc supplements are used extensively in medicine and research and for public health purposes in the prevention and treatment of zinc deficiency. However, little is known about the efficiency of zinc utilization after different doses. OBJECTIVE The objective was to determine the relation between dose of aqueous zinc and absorbed zinc (AZ) in healthy adults. DESIGN Eight healthy a...

Millet is unusually drought resistant and consequently there is a progressive increase in the use of these grains as a human food staple, especially in large areas of India and sub-Saharan Africa. The purpose of this study was to determine the absorption of iron and zinc from pearl millet biofortified with 2 micronutrients that are typically deficient in nonfortified, plant-based diets globally...

An experiment was conducted with rats to determine the effects on the tissue concentrations of Zn, Fe, Cu, and Mg of feeding various amounts of zinc. The rats were pair-fed one of the following diets for four weeks: Diet A, a zinc-deficient diet; a diet containing the recommended amoun of zinc (diet A plus 55 microgram of zinc per gram of diet), or diet A plus 550 microgram zinc per gram of die...

SCOPE Worldwide geographical variation in cancer incidence indicates a correlation between dietary habits and cancer risk. Epidemiological studies have suggested that populations with high isoflavone intake through soy consumption have lower rates of breast, prostate, and colon cancer. Isoflavone genistein in soybean is considered a potent chemopreventive agent against cancer. Although several ...

INTRODUCTION Atopic dermatitis (AD) is a chronic, pruritic inflammatory disease, characterized by a relapsing-remitting course. The pathogenesis of atopic dermatitis is not completely understood, although the disorder appears to result from the complex interaction between immune abnormalities, genetic and environmental factors. Trace elements are essential for normal functioning of the immune s...

Iron and zinc are currently the trace minerals of greatest concern when considering the nutritional value of vegetarian diets. With elimination of meat and increased intake of phytate-containing legumes and whole grains, the absorption of both iron and zinc is lower with vegetarian than with nonvegetarian, diets. The health consequences of lower iron and zinc bioavailability are not clear, espe...