The purpose of this study was to compare the metabolic properties of maintenance hemodialysis patients treated with glucose-containing and glucose-free dialysate using metabonomics. Pre- and post-dialysis serum samples from group G (-) using glucose-free dialysate, and group G (+) using glucose-added dialysate (glucose levels were 5.5 mmol/L) were analyzed and tested with high performance liqui...

Hyperchloremia is one of the multiple etiologies of metabolic acidosis in hemodialysis (HD) patients. The aim of the present study was to determine the influence of chloride dialysate on metabolic acidosis control in this population. We enrolled 30 patients in maintenance HD program with a standard base excess (SBE) ≤2 mEq/L and urine output of less than 100 mL/24 h. The patients underwent dial...

1. In eight patients being treated by chronic dialysis the relation of magnesium metabolism to the magnesium concentration of the dialysate was investigated. During four periods of 2-6 weeks the magnesium concentrations of the dialysis fluid were 0'44±0'15 mg/IOO ml, 0'70±0'24 mg/IOO ml, 1'83±0'18 mg/IOO ml and 1'97±0'21 mg/IOO ml. 2. During all periods the concentration of plasma magnesium and...

We conducted a prospective, randomized study to compare conventional continuous venovenous hemodiafiltration (CVVHDF) with sustained hemodiafiltration (SHDF) using an acetate-free dialysate. Fifty critically ill patients with acute kidney injury (AKI) who required renal replacement therapy were treated with either CVVHDF or SHDF. CVVDHF was performed using a conventional dialysate with an efflu...

Received 8/30/2000; accepted 9/18/2000. For Correspondence or reprints contact: Nan-Tsing Chiu, M.D., Department of Nuclear Medicine, National Cheng Kung University Hospital, 138, Shing-Li Road, Tainan 704, Taiwan. Tel:(886)6-2353535 ext. 2480 Fax: (886)6-2766609 E mail: [email protected] Background: Continuous ambulatory peritoneal dialysis (CAPD) has several advantages. However, some co...

BACKGROUND/AIMS We assessed changes in hemodynamic and arterial stiffness parameters following reductions of dialysate calcium concentrations in patients undergoing hemodialysis. METHODS In this prospective study, 20 patients on maintenance hemodialysis (10 females, 10 males) with dialysate calcium concentrations of 1.75 mmol/L were enrolled. At the start of the study, the dialysate calcium l...

BACKGROUND Sodium thiosulfate therapy has been proposed for calcific uremic arteriolopathy and nephrogenic systemic fibrosis in hemodialysis patients. The treatment brings 3.7 g (161 mmol) of sodium. How to counterbalance this sodium load was studied. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Plasma conductivity (Cp) and mass balance index were compared for 20 sessions without thiosulfate...

The leakage of dialysate is an uncommon complication in peritoneal dialysis. Here we report a 56-year-old man with uremia on continuous ambulatory per itoneal dialysis (CAPD) presenting with acute and severe scrotal swelling. Significantly elevated blood pressure, increased abdominal girth, reduced ultraf i ltrat ion and weight gain of two kilograms developed within one day. Computed tomographi...

clarify if the spectrophotometric analysis of spent dialysate may allow the possibility to monitor the removal of β2M during HD. These results were obtained from the analyses of serum and spent dialysate samples of the 22 MHD patients (16 men, 6 women) of a previous study, where we confirmed the possibility to monitor the removal of small molecules, namely uric acid, by spectrophotometric analy...

CAPD patients given lercanidipine developed non-infective turbid peritoneal dialysis. Differential diagnosis of non-infectious cloudy peritoneal dialysate includes cellular causes (i.e. leucocyte, eosinophils, red cells and malign cells) and non-cellular causes (i.e. triglyceride and drugs) [2]. Yoshimoto et al. [1,3] reported that benidipine, manidipine, nisoldipine and nifedipine caused cloud...