introduction: tympanoplasty is the standard and well established procedure for closure of tympanic membrane perforations .this paper compares the results of tympanoplasty in terms of hearing improvement and graft incorporation in patients with chronic perforation of the tympanic membrane between two groups with and without active drainage at the time of surgery.  materials and methods: sixty re...

introduction: nodular fasciitis is described as a benign reactive proliferation of myofibroblasts. due to its rapid-growing nature, a precise clinical diagnosis is difficult and the condition is frequently misdiagnosed as malignant lesions.   case report: in this study, we present the case of a young woman with an auricular nodular fasciitis as an example of one of the rarest sites of this tumo...

ear candling is an alternative medicine practice alleged to enhance general health by putting an end of a hollow candle in the ear canal and lighting up the other end of it. it also is advertised for cerumen and debris (bacteria and fungi) removal. ear candling is claimed to create negative pressure for drawing cerumen from the ear and to benefit the ears in many ways. it is however not free of...

Gene-based therapeutics are being developed as novel treatments for genetic hearing loss. One roadblock to effective gene therapy is the identification of vectors which will safely deliver therapeutics to targeted cells. The cellular heterogeneity that exists within the cochlea makes viral tropism a vital consideration for effective inner ear gene therapy. There are compelling reasons to identi...

Neurotrophic factors (NTF) play key roles in the survival of neurons, making them promising candidates for therapy neurodegenerative diseases. In case inner ear, sensorineural hearing loss (SNHL) is characterized over time by a degeneration primary auditory spiral ganglion neurons (SGN). It well known that selected NTF can protect SGN from degeneration, which positively influences outcome cochl...