نتایج جستجو برای: enterovirus 71

تعداد نتایج: 63714  

Ahmad Nejati, Alisha Akya Azam Elahi Farhad Babaei, Mohsen Moghoofei, Roya Chegenelorestani

Background: Aseptic meningitis is frequently caused by viral agents, particularly human enterovirus. Several methods of Reverse Transcription PCR(RT-PCR) have recently been introduced and modified for better diagnosis of enteroviral infection in meningitis. This study aimed to determine enteroviruses in patients with suspicion of aseptic meningitis using RT-PCR in the West of I...

Journal: :International journal of clinical and experimental pathology 2014
Lulu Gao Peixin Lin Shuguang Liu Bin Lei Qing Chen Shouyi Yu Hong Shen

We report an 8-month-old female infant with the fatal enterovirus 71 infection here. Clinically, she developed respiratory failure and severe pulmonary edema rapidly. Histologically, the lung specimen showed diffuse, severe pulmonary congestion and edema with focal intra-alveolar hemorrhage and typical features of acute encephalitis were easily identified under light microscope. Immunohistochem...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2002
Tzou-Yien Lin Luan-Yin Chang Shao-Hsuan Hsia Yhu-Chering Huang Cheng-Hsun Chiu Chuen Hsueh Shin-Ru Shih Ching-Chuan Liu Mei-Hwan Wu

The most recently discovered enterovirus, enterovirus 71 (EV71), is neurotropic and may cause severe disease and sudden death in children. In 1998, a large outbreak of enterovirus infection occurred in Taiwan that resulted in 405 severe cases in children and 78 deaths. Of the 78 children who died, 71 (91%) were <5 years old. EV71 was the primary agent in fatal cases of infection. Most of these ...

Journal: :Antimicrobial agents and chemotherapy 2004
Shin-Ru Shih Mun-Chung Tsai Sung-Nien Tseng Kuo-Fang Won Kak-Shan Shia Wen-Tai Li Jyh-Haur Chern Guang-Wu Chen Chung-Chi Lee Yen-Chun Lee Kuan-Chang Peng Yu-Sheng Chao

Enterovirus 71 is one of the most important pathogens in the family of Picornaviridae that can cause severe complications in the postpoliovirus era, such as encephalitis, pulmonary edema, and even death. Pyridyl imidazolidinone is a novel class of potent and selective human enterovirus 71 inhibitor. Pyridyl imidazolidinone was identified by using computer-assisted drug design. This virologic in...

Journal: :Journal of Microbiology, Immunology and Infection 2015

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