Diethyldithiocarbamate (DDC), a potent copper chelating agent, has long been used for the treatment of oxygen toxicity to the central nervous system, as an immunomodulator to treat cancer, and in HIV-infected patients. We evaluated the antioxidant properties of DDC, including its scavenging of reactive oxygen species, its reducing properties, its iron-chelating properties, and its protective ef...

a simple ion imprinted amino-functionalized sorbent was synthesized by coupling activated carbon with iminodiacetic acid, a functional compound for metal chelating, through cyanoric chloride spacer. the resulting sorbent has been characterized using fourier transform infrared spectroscopy (ft-ir), elemental analysis, thermogravimetric analysis (tga) and evaluated for the preconcentration and de...

A method for direct, continuous determination of ferric ions produced in autotrophic iron oxidation, which depends upon the measurement of ferric ion absorbance at 304 nm, is described. The use of initial rates is shown to compensate for such changes in extinction during oxidation, which are due to dependence of the extinction coefficient on the ratio of complexing anions to ferric ions. A grap...

A major process of iron homeostasis in whole-body iron metabolism is the release of iron from the macrophages of the reticuloendothelial system. Macrophages recognize and phagocytose senescent or damaged erythrocytes. Then, they process the heme iron, which is returned to the circulation for reutilization by red blood cell precursors during erythropoiesis. The amount of iron released, compared ...

Objective Iron overload in the body is related with toxic effects and threatens the health. The aim of this study was to evaluate the protective role of hydroalcoholic extract of ginger (Zingiber officinale) against ferrous sulfate-induced hepatic and renal functional disorders and histological damages in rats. Materials and Methods The rats were divided into four groups (n=7): Sham, Sham + G...

1. During pathological states of iron-overload or oxidant stress, low-molecular-mass iron can become available within extracellular fluids. 2. This iron would be converted to the ferrous state were it not for the protective anti-oxidant protein caeruloplasmin. 3. The ferrous-ion-oxidizing activity of caeruloplasmin rapidly converts ferrous ions back to the less reactive ferric state so that the...

Korean fir (Abies koreana Wilson) is traditionally used in folk medicine for its antibacterial, memory-enhancing, and anti-inflammatory properties. In this study, we evaluated the antioxidant skin-whitening effects of methanol ethanol extracts needles. The were tested their capacity using various assays, including radical scavenging (1,1-diphenyl-2-picrylhydrazyl, O2-, H2O2 NOž), SOD-like, ferr...

Bioflavonoids such as hesperidin and hesperetin anticancer antioxidant agents are widely used in the formulation of many herbal drugs. Recently, promising evidence for prevention treatment COVID 19 using these compounds has been reported. Unfortunately, often insoluble aqueous media have low stability gastric acid environment. These factors reduced bioavailability related oral dosage forms dige...