Assessing the contributions of individual components in multi-component interventions poses complex challenges for prevention researchers. We review the strengths and weaknesses of designs and analyses that may be useful in answering three questions: (1) Is each of the individual components contributing to the outcome? (2) Is the program optimal? and (3), Through what processes are the componen...

Foldover is a widely used procedure for selecting follow-up experimental runs. As foldover designs require twice as many runs as the initial design, they can be inefficient if the number of effects to be dealiased is smaller than the size of the original experiment. Semifolding refers to adding half of a foldover fraction and is a technique that has been investigated in recent literature for re...

This paper addresses the problem of optimizing a factorial system with multiple responses. A heuristic termed probabilistic sequential methodology (PSM) is proposed. The PSMidenti® es those designs that maximize the likelihood of satisfying a given set of functional requirements. It is based on sequential experimentation, statistical inference and a probabilistic local search. The PSM comprises...