The haywire gene of Drosophila encodes a putative helicase essential for transcription and nucleotide excision repair. A haywire allele encoding a dominant acting poison product, lethal alleles, and viable but UV-sensitive alleles isolated as revertants of the dominant acting poison allele were molecularly characterized. Sequence analysis of lethal haywire alleles revealed the importance of the...

today, in a competitive market, service organizations and producers have a great attention to optimization and customer satisfaction in order to become competitive. service organization must reduce the number of arrival, waiting time and service time in the queue to increase the customer satisfaction. in this paper by the aim of queuing theory we analyze the optimal amount of increment in a rep...

Although a large literature exists on the repair and deterioration of machines, the associated problem of maintenance schedules for deteriorating renewable facilities has been little studied. These facilities include all those which can be restored to a near-new state by renovation or rebuilding, so that the market value and performance of the facility depends on the current state of repair rat...

In this paper authors have considered a system having three units A, B1 and B2. A is controlled by a controller and B1 and B2 are independent. Two repairmen are involved in repair of the system. One of the repairmen (the first) is the foreman (boss) and the other an assistant (apprentice). Whenever any unit fails, repair is undertaken by boss. If the boss is busy in repairing and at the same ti...

This paper analyzes a controllable discrete-time machine repair problem withL operating machines and two repairmen. The number of working servers can be adjusteddepending on the number of failed machines in the system one at a time at machine's failure orat service completion epochs. Analytical closed-form solutions of the stationary probabilities ofthe number of failed machines in the system a...

A dominant narrative surrounding smartphone lifespans suggests that their objective functional capabilities deteriorate rapidly and if only devices were more repairable consumers would use them longer thereby reducing demand for new production e-waste generation. Here we a big-data approach to help unpack this examine two related yet distinct aspects: performance obsolescence, interest in repai...

Objective(s): Tendon healing is substantially slow and often associated with suboptimal repair. Cell therapy is one of the promising methods to improve tendon repair. Blastema, a population of undifferentiated cells, represents characteristics of pluripotent mesenchymal stem cells and has the potentials to be used in regenerative medicine. The aim of this study was to ...

We consider a single-server queueing system with Poisson arrivals and general service times. While the server is up, it is subject to breakdowns according to a Poisson process. When the server breaks down, we may either repair the server immediately or postpone the repair until some future point in time. The operating costs of the system include customer holding costs, repair costs and running ...