Introduction: Bread making quality is affected by gluten genes and balance between their expressions. Hence, it is necessary for a comprehensive research to study and compare all gluten genes and their regulating elements simultaneously. Objectives: The aim of this study was to evaluate the molecular mechanism of bread quality in the level of coding genes and regulating elements via compa...

background: in order to select a better antibiotic choice for treatment of pseudomonas aeruginosa infections, this study was conducted to determine the frequency of resistance to some antipseudomonal β-lactams in p. aeruginosa isolates from patients in tehran, iran. in addition, the relation between presence of genes known to be responsible for resistance to β-lactams (ampc, mexc1,2,and mexc3,4...

the aim of this study was to identify virulent shiga toxin-producing escherichia coli (stec) strains isolated from faecal samples of 100 clinically healthy calves. in the present study, a total of 100 escherichia coli (e. coli) isolates from clinically healthy calves belonging to 6 different farms located in khorasan razavi province, iran, were examined for presence of virulence genes character...

intoduction: acute myeloid leukemia (aml) is a heterogeneous group of hematologic malignancies with abundant changeability in the pathogenesis. dna methylation of cpg islands within the promoters of specific genes may play roles in tumor initiation and progression. secreted frizzled-related proteins (sfrps) are negative regulator of the wnt signaling pathway. in the present study, we examined t...

Background: Acute lymphoblastic leukemia (ALL) as the most common malignancy in children is associated with high mortality and significant relapse. Currently, the non-invasive diagnosis of pediatric ALL is a main challenge in the early detection of patients. In the present study, a systems biology approach was used through network-based analysis to identify the key candidate genes related to AL...

wheat is a crop with spring and winter types and wide adaptability to different climate conditions. the wide adaptability of wheat is mainly controlled by three groups of genetic factors and among them vernalization (vrn) genes play pivotal role in determining spring and winter types. in this study, 395 iranian wheat landraces were characterized with specific primer pairs designed based on vrn-...

resistance gene analog polymorphism (rgap) markers linked to fusarium head blight resistance (fhb) and co-localize with qfhs.ndsu-3bs were identified using f3 plants and f3:5 lines derived from a ‘wangshuibai’ (resistant) / ‘seri82’ (susceptible) cross. the mapping populations were genotyped using 50 degenerate primers designed based on the known r genes. out of the 50 designed primer combinati...

Objective(s): The aim of this study was to investigate the methylation status and mRNA expression levels of P15, death-associated protein kinase (DAPK), and suppressor of cytokine signaling-1 (SOCS1) genes in multiple myeloma (MM). Materials and Methods: The bone marrow samples of 54 MM patients were collected and the methylation status of the P15, DAPK, and SOCS1 gene promoter regions was dete...