Toxicological studies constitute an essential part of the effort in developing an herbal medicine into a drug product. A newly developed thymoquinone-rich fraction nanoemulsion (TQRFNE) has been prepared using a high pressure homogenizer. The purpose of this study was to investigate the potential acute toxicity of this nanoemulsion in Sprague Dawley rats. The acute toxicity studies were conduct...

The most commonly used cell disruption procedures may present lack of reproducibility, which introduces significant errors in the quantification of intracellular components. In this work, an approach consisting in the definition of an overall key performance indicator (KPI) was implemented for a lab scale high-pressure homogenizer (HPH) in order to determine the disruption settings that allow t...

We have proposed a fruitful design principle targeting concentration ratio (CR) >1000× for typical high concentrating photovoltaics (HCPV) system, on account of two-concentrator system + homogenizer. The primary dual-lens concentrator unit, completely analogous basic optics seen in the superposition compound eyes, is trend not hitherto reported solar concentrators to our knowledge. Such cons...

background and aim: menopause refers to the cessation of menstruation due to hormonal changes and ovarian inactivity in women. these changes in hormone levels lead to various health consequences. this period of physiological changes usually starts in women with 40-50 years of age, and is characterized by the reduction of estrogen level. the mortality rate of premenopausal women, due to cardiova...