It was aimed to investigate the association of the synapsin III gene -196 G> A and -631 C>G polymorphisms that takes place in an encoding presynaptic protein, with adult attention deficit hyperactivity disorder (ADHD). One hundred thirty-nine patients having adult ADHD and 106 controls were included in the study. DNA samples were extracted from whole blood and genetic analyses were performed. A...

Using DNA probes in a structural study of the antithrombin III gene locus we found no evidence of gene deletion in two British kindreds with inherited antithrombin III deficiency. However, linkage analysis between a common DNA polymorphism and the antithrombin III deficiency trait showed that the defect lies at or close to the antithrombin III structural gene. The lod score for linkage within t...

Inflammatory changes in the gastric mucosa are commonly observed in Japanese patients with functional dyspepsia (FD). However, detailed data regarding the relationship between the genetic regulatory factors of inflammation and FD are not available. CD14 is an important mediator of the inflammatory response in the first line of host defense by recognition of Lipopolysaccharide (LPS). We aimed to...

BACKGROUND Gliomas account for almost 80% of primary malignant brain tumors. Epidermal growth factor (EGF) is an interesting research candidate in which to look for genetic polymorphisms because of its role in mitogenesis and proliferation. Extensive studies have found that a single nucleotide polymorphism (SNP) +61 G/A (rs4444903) in the EGF gene is associated with the susceptibility of glioma...

In the early embryo the allantois, which lies in the body stalk, is situated at the hind end of the foetus and is at first meirely a continuation of the hind gut. As growth proceeds, the hind end of the embryo assumes a curvature and the allantois and body stalk are displaced ventrally. The differentiation of the allantois and hind gut is now easy to see and the sharp bend between the two becom...

background: endometriosis is one of the most commonly encountered benign problems in gynaecology. it is frequently associated with chronic pelvic pain, dysmenorrhoea, menorrhagia and dyspareunia, which lead to infertility. we determined the possible association between cyp1a1 mspi and gstm1 null polymorphism in the pathogenesis of endometriosis. materials and methods: ninety seven cases of endo...

Purpose: A let-7 microRNA-complementary site (LCS6) polymorphism in the 30 untranslated region of the KRAS gene has been shown to disrupt let-7 binding and upregulate KRAS expression. We evaluated the LCS6 genotype and its association with KRASmutation status, clinicopathologic features, and disease-free survival (DFS) in patients with stage III colon cancer who enrolled in a phase III clinical...

background and objectives: to investigate coagulase gene polymorphisms of mrsa and mssa isolates from shiraz teaching hospitals from 2011 to 2012. materials and methods: a total of 302 isolates of staphylococcus aureus were collected from clinical specimens in three major teaching hospitals and confirmed on the basis of morphological characteristics and biochemical tests. the isolates were subj...

In my earlier experiments with spinal cats (1962) I established that the isolated lumbosacral cord is able to co-ordinate walking movements of the hind limbs. In cats this part of the cord possesses a high degree of autonomy. It seemed interesting to know whether in rabbits the isolated lumbosacral cord is also able to maintain these functions. It was especially important to establish whether t...

This paper describes previously unreported malformations of both fore and hind feet in a liveborn common marmoset. Ectrodactyly of both fore feet and left hind foot and syndactyly of the right hind foot were observed.