نتایج جستجو برای: homocysteine blood

تعداد نتایج: 694639  

Journal: :Journal of family & reproductive health 2015
Soheila Riahinejad Ahmad Mirdamadi Elham Alizadeh

OBJECTIVE Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women. Metformin is a biguanide commonly used to improve PCOS symptoms. Effect of metformin on the levels of serum homocysteine (Hcy) in PCOS women is unclear. The aim of this study is evaluating the effect of metformin administration on serum Hcy levels and metabolic parameters of PCOS patients. MATER...

Mohammad Ali Sardar Mohsen Nematy, Samaneh Farahati Seyyed Reza Attarzadeh Hosseini

Introduction: Increased levels of certain markers like fibrinogen and Homocysteine are independently associated with an increased risk of cardiovascular diseases. Considering the numerous favorable effects of healthful nutrition and physical activity on reducing the risk of atherosclerosis, in this study we intend to take into account fasting and physical activity during the month of Ramadan an...

Journal: :Clinical science 2003
Maarten T M Raijmakers Geurt W Schilders Eva Maria Roes Lambertus J H van Tits Heidy L M Hak-Lemmers Eric A P Steegers Wilbert H M Peters

Methionine loading seems to be accompanied by increased oxidative stress and damage. However, it is not known how this oxidative stress is generated. We performed the present crossover study to further elucidate the effects of methionine loading on oxidative stress in the blood of healthy volunteers, and to examine possible preventative effects of N -acetylcysteine (NAC) administration. A total...

Journal: :Clinical chemistry and laboratory medicine 2005
Katharina Schroecksnadel Christiana Winkler Barbara Wirleitner Harald Schennach Günter Weiss Dietmar Fuchs

Inflammation, immune activation and oxidative stress play a major role in the pathogenesis of cardiovascular disorders. In addition to markers of inflammation, moderate hyperhomocysteinemia is an independent risk factor for cardiovascular disease, and there is a link between the activation of immunocompetent cells and the enhanced formation of homocysteine in vitro. Likewise, anti-inflammatory ...

Journal: :JPMA. The Journal of the Pakistan Medical Association 2007
Nevin Sanlier Nurcan Yabanci

OBJECTIVE To determine the effects of obesity on blood lipids and homocysteine levels of university students. METHODS The study comprised of 172 male and 183 female students who were classified according to their body mass index (BMI) into 3 groups as underweight, normal weight and overweight. Anthropometric measurements, blood lipids and homocysteine levels were analyzed. RESULTS Mean fat ...

Journal: :Clinical science 2005
Frank Stam Yvo M Smulders Coen van Guldener Cornelis Jakobs Coen D A Stehouwer Kees de Meer

Folic acid treatment decreases plasma total homocysteine concentrations in healthy subjects, but the effects on homocysteine metabolism are unknown. In the present study, we investigated the effect of 3 weeks of oral treatment with 5 mg of folic acid on one-carbon flux rates in 12 healthy subjects, using in vivo stable isotope methods. In addition, we determined the effect of folic acid on bloo...

Journal: :Seizure 2006
Ufuk Sener Yasar Zorlu Oguz Karaguzel Ozlem Ozdamar Isıl Coker Murat Topbas

There is emerging evidence to support the unfavorable effects of some anti-epileptic drugs on the plasma homocysteine concentrations. Elevated homocysteine levels induced by anti-epileptic drug administration can theoretically increase not only the risk of vascular occlusive diseases, but also the risk of resistance to anti-epileptics and development of refractory epilepsy. To investigate the e...

Journal: :Indian journal of pharmacy and pharmacology 2023

Hyperhomocysteinemia is a condition characterized by elevated levels of homocysteine in the blood, which has been linked to various cardiovascular and renal complications, including impaired function. , widely used medicinal herb, shown possess antioxidant, anti-inflammatory, vasoprotective properties. However, its potential role improving function hyperhomocysteinemic conditions remains largel...

Journal: :Journal of nutritional science and vitaminology 2011
Siew-Choo Chew Geok-Lin Khor Su-Peng Loh

Folate is of prime interest among investigators in nutrition due to its multiple roles in maintaining health, especially in preventing neural tube defects and reducing the risk of cardiovascular diseases. We investigated the effect of dietary folate intake on blood folate, vitamin B(12), vitamin B(6), and homocysteine status. One hundred subjects consisting of Chinese and Malay subjects volunte...

2013
Ayami Kume Kayo Kurotani Masao Sato Yuko Ejima Ngoc Minh Pham Akiko Nanri Keisuke Kuwahara Tetsuya Mizoue

BACKGROUND Supplementation studies have suggested a role of n-3 polyunsaturated fatty acids (PUFAs) in homocysteine metabolism, but the evidence is limited and inconsistent among studies that measured blood levels of n-3 and n-6 PUFAs. We examined the association between blood levels of PUFAs and homocysteine in Japanese men and women. METHODS The subjects were 496 employees (290 men and 206 ...

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