The routine metabolic rate of Pseudocrenilabrus multicolor victoriae, laboratory-reared, F1 offspring of parents collected from a hypoxic swamp, did not differ between sibs raised under normoxia and hypoxia. In the offspring of parents originating from a river where the oxygen levels were generally high but fluctuating, the metabolic rate of fish raised under normoxia was higher than for sibs r...

Objective(s): Thyroid hormones play an essential role in fetal growth and maternal hypo-thyroidism which leads to cardiovascular deficiency in their offspring.  Considering this, we intended to investigate the impact of gestational hypothyroidism on offspring vascular contractibility and possible underlying mechanisms. Materials and Methods: Hypothyroidism was induced in female rats by administ...

To discuss the psychological impact of disclosure decisions on donor gamete participants including gamete donors, intended parents, and the children conceived through these third party reproductive techniques. In the past decade, there has been a dramatic increase worldwide in the number of children born as a result of gamete donation. The growing demand for these programs has resulted in a tre...

Early-life experiences with caregivers can significantly affect offspring development in human and non-human animals. While much of our knowledge of parent-offspring relationships stem from mother-offspring interactions, increasing evidence suggests interactions with the father are equally as important and can prevent social, behavioral, and neurological impairments that may appear early in lif...

Maternal health during gestational period is undoubtedly critical in shaping optimal fetal development and future of the offspring. Gestational diabetes mellitus a metabolic disorder occurring pregnancy with an alarming increasing incidence worldwide recent years. Over years, there growing body evidence that uncontrolled maternal hyperglycaemia can potentially have detrimental effect on neurode...

BACKGROUND The transgenerational metabolic effects of betel-quid chewing have been reported in mice but not in humans. OBJECTIVE This study aimed to determine whether exposure to paternal chewing of betel nut quids led to an increased risk of early manifestation of the metabolic syndrome (MetS) in human offspring. DESIGN The subjects were selected from 66,971 residents aged >19 y who attend...

Obesity and related comorbidities are becoming increasingly prevalent globally. In mice preconception paternal exposure to a high fat diet (HFD) impairs the metabolic and reproductive health of male offspring, despite their control diet (CD) consumption. However, offspring share lifestyle, including diet, with parents. We assessed if male offspring from HFD fathers have a heightened susceptibil...

background: health status of offspring is programmed by maternal diet throughout gestation and lactation. the present study investigates the lasting effects of maternal supplementation with different amounts of soy oil or extra virgin olive oil (evoo) on weight and biochemical parameters during gestation and lactation of female mice offspring. methods: eight weeks old female c57bl/6 mice (n=40)...