This thesis investigated the impact of manufacturing process modifications for the bulk manufacture of curcumin implants for diabetic neuropathy pain relief. A homogeneous mixture of poly(caprolactone) (PCL) and curcumin was blended using cryomilling as an alternative to the solvent mixing method. Cryomilling was selected due to its faster processing time and reduced cost of materials in compar...

the subject of geometry and proportions has been regarded as an issue which has a close relationship with architecture. since the entire universe, living beings and the human geometry can be seen clearly, that’s why our unconscious essence has accustomed to these proportions whereby reflection of this mentality can be seen in the architect’s hands and thought in the architecture. it can witness...

background and aims. resonance frequency analysis (rfa) offers a noninvasive clinical measurement of stability and osseointegration of implants; it is a useful tool to establish implant loading time. the rfa values are represented by a quantitative unit called the implant stability quotient (isq) on a scale from 1 to 100. the aim of the present study was to measure the stability of astra tech a...

Introduction: The survival of an implant system is affected by the choice of antirotational design, which can include an external or internal hex. Implant success also is affected by the maintenance of the crestal bone around implants. The aim of present study was to evaluate the crestal bone loss and clinical parameters related to bone loss in patients loaded with an external or internal hex 3...

This work presents a numerical approach in order to predict the influence of implant material stiffness in a femoral component design when submitted in compression. The implant success depends on the transferred load to the neighboring bone. The finite element method can be used to analysis the stress and strain distribution in the femoral component allowing to improve the implant selection. Fo...

background: fracture load of implant-supported restorations is an important factor in clinical success. this study evaluated the effect of two techniques for screw access hole preparation on the fracture load of cement-screw retained implant-supported zirconia-based crowns. methods: thirty similar cement-screw retained implant-supported zirconia-based maxillary central incisor crowns were evalu...

peri-implantitis is a site-specifi c infectious disease that causes an infl ammatory process in soft tissues, and bone loss around an osseointegrated implant in function. the etiology of the implant infection is conditioned by the status of the tissue surrounding the implant, implant design, degree of roughness, external morphology, and excessive mechanical load. the microorganisms most commonl...