The RBC from mice of certain inbred strains hemolyzed under oxidative stress (2.0 mmol/L hydrogen peroxide), whereas red cells from mice of other strains did not. In the experimental system human erythrocytes did not hemolyze. The rate of formation of malonyldialdehyde (a fatty acid oxidative breakdown product) was fourfold higher in hemolytic v nonhemolytic red cells. There was insufficient va...

Neonatal gonadeetomy has been used in some inbred strains of mice (7, 8, 10, 13-17) as an experimental tool to study the effect of hormonal imbalance. ~I'he effect of neonatal gonadectomy in reciprocal hybrid mice of several inbred strains has been described (11, 1~). This paper will report the response to gonadectomy of the F1 animals of strain DE X strain DBA and will compare the response of ...

B ETWEEN 1938 and 1949 seven different unrelated inbred lines of Duroc swine were developed by the Oklahoma Agricultural Experiment Station in cooperation with the Regional Swine Breeding Laboratory. In sixteen of the twenty-two farrowing seasons from the spring of 1939 through the fall of 1949, both inbred and two-line-cross litters were produced. In some seasons outbred Duroc and three-linecr...

tniarylmethane dyes' was tested by oral adminis tration to three types of tumor-bearing animals: mice of inbred strains bearing 100 per cent trans plantable carcinomas and sarcomas; rats of inbred strains bearing 100 per cent transplantable san comas, and commercial as well as inbred strains of mice bearing 100 per cent transplantable ascites tumor. The present report is concerned with the effe...